Pediatric Urinary System, Adrenals, and Retroperitoneum Flashcards
At what age are kidneys a similar size to adults?
> 15 yrs
SF of pediatric kidneys
- Prominent renal pyramids
- Increased echogenicity of cortex
- Irregular renal outlines due to lobulations
- Should not be a difference of >2cm between kidneys
What is another term for renal junctional defect?
Interrenucular defect - prominent renal lobulation
SF of renal junctional defect?
Triangular echogenic indentation of cortex
What are column of bertin?
Extension of the cortex that separates the pyramids - cortical tissue invaginating renal sinus
What should the renal pelvis typically measure?
<10mm
What is another name for bilateral renal agenesis?
Potter syndrome
What should you suspect with a “lying down adrenal sign”?
No kidney within the renal fossa - absent kidney
What is the most common palpable mass in neonates and most common renal anomaly diagnosed in infants?
Hydronephrosis
What is hydronephrosis most commonly caused by?
Obstruction - UPJ
Signs and symptoms of hydro?
- Palpable abdominal mass
- Flank pain
- Hematuria
- UTI’s (often recurring)
Hydronephrosis grading?
Grade 1: Small, fluid-filled separation of the renal pelvis
Grade 2: Dilation of some but not all calyces; renal sinus orientation still concave
Grade 3: Complete pelvocaliectasis; calyx presentation is changed in convex.
Grade 4: Prominent dilation of collecting system; thinning of renal parenchyma; no differentiation between the collecting system and renal parenchyma
What is a common NON-obstructive cause of hydro?
VUR - vesicoureteral reflux
What is the most common site of obstruction in the kidneys?
UPJ obstruction
Is UPJ obstruction more common in males or females?
Males
What is the second most common cause of pediatric hydronephrosis in peds?
Distal ureteral obstruction
Signs and symptoms of distal ureteral obstruction?
Recurring UTI’s
What is the most common congenital anomaly of GU tract?
Duplicated collecting system - the 3rd most common cause of hydro
What is a common complication of a duplicated collecting system?
Ureterocele
Is duplicated collecting system more common in males or females and is it unilateral or bilateral?
Females - bilateral
What is a common location of the kidneys with horseshoe kidney?
Lower and are medially rotated - anterior to the Ao
What is known as a fold or flap of tissue in the urethra causes the obstruction?
PUV
What is the most common cause of urethral obstruction in boys?
PUV
What are PUV associated with?
Prune Belly Syndrome
SF of PUV?
- Bilateral hydro w/ parenchymal thinning
- Possible dysplastic kidneys with increased
parenchymal echogenicity and cysts - Bilateral tortuous dilated ureters
- Thick bladder walls
- Key hole sign: visualization of dilated posterior urethra
What abnormality is associated with the “key hole sign” ?
PUV
What is prune belly also called?
Eagle Barrett
Classic triad of prune belly?
- Absent abdominal muscles
- Urinary tract abnormalities
- Cryptorchidism
SF of prune belly?
- Flaccid dilated bladder
- Small cystic dysplastic kidneys or hydronephrotic kidneys
What is the cause of medullary cystic disease in young adults?
Metabolic dysfunction
What are the two types of medullary cystic disease?
- Medullary sponge kidney AKA renal collecting tubular ectasia
- Juvenile nephronopthisis AKA uremic medullary kidney disease
12 year old patient presents with bilateral echogenic renal pyramids. What is the likely diagnosis?
Medullary sponge kidney
Patient presents with small echogenic kidneys and a loss of the CMJ. What is the likely diagnosis?
Juvenile nephropthisis AKA uremic medullary kidney disease
What is the most common cystic dysplasia?
MCDK
What is the 2nd most common cause of an abdominal mass in newborns after hydro?
MCDK
What is the etiology of MCDK?
Complete ureteral obstruction in utero
T or F? MCDK does not have communication between cysts?
TRUE
What are the two types of polycystic kidney disease?
Infantile PKD (ARPKD) and Adult PKD (ADPKD)
SF of infantile PKD?
Bilateral, echogenic, enlarged kidneys
What abnormality is associated with infantile PKD?
Hepatic fibrosis - can later on cause renal failure or liver failure
What is the most common SF of ADPKD?
Renal enlargement - usually bilateral
What is known as cystic dilation of bowman’s capsule and normal tubules?
Glomerular cystic disease
What is the most common malignant renal tumour in peds?
Nephroblastoma/Wilm’s tumour
What is the most common SOLID abdominal tumour in children?
Nephroblastoma/Wilm’s tumour
What pathology is associated with anirida and BWS?
Nephroblastoma/Wilm’s tumour
Nephroblastoma’s frequently invade what structures?
IVC and renal vein - mets occurs to liver and lungs
SF of nephroblastoma?
- Large well-circumscribed smooth homogenous mass
- Hyperechoic
- May contain hypoechoic or cystic areas
What is a precursor to Wilm’s tumour?
Nephroblastomatosis
SF of multilocular cystic nephroma?
- Mass with multiple cysts that have septations
- Normal renal parenchyma may be present elsewhere and is sharply demarcated from the mass
What is the most common abdominal neoplasm seen in the neonate?
Mesoblastic nephroma
T or F? Mesoblastic nephroma’s have malignant potential?
TRUE
SF of mesoblastic nephroma?
- Resembles Wilm’s tumour
- Homogenous / hyperechoic
- May be heterogeneous w/ areas of necrosis & hemorrhage centrally (usually 5-8cm)
What is RCC associated with (2)?
- Tuberous sclerosis
- Von-hippel lindau
AML’s can be associated with what?
Tuberous sclerosis
SF of chronic pyelonephritis?
- Small kidney,
- Increase echogenicity
- Irregular shape due to focal parenchymal loss & scarring
Renal scarring is typically due to what?
Chronic infection
What pathology is known as a deposit of calcium in the kidney?
Nephrocalcinosis
SF of renal vein thrombosis?
- Enlarged kidneys
- Possible thrombus in renal vein or IVC
What is the most common urinary tract infection in children?
Cystits - 10x more common in girld
SF of cystitis?
1.Bladder wall thickening (>3mm when full bladder or 5mm when empty)
- Typically diffuse but can be focal/asymmetrical (suggestive of a mass.. f/u after treatment to see if resolved)
- Hyperemia of bladder wall
The urachus is a tubular structure continuous with what?
Anterior bladder extending to the umbilicus
What is the most common urachal variant?
Patent urachus - patent lumen causing urine to drain from umbilicus
Urachal sinus vs diverticulum
Sinus - urachus CLOSES at bladder but not umbilicus
Diverticulum - urachus CLOSES at umbilicus but not bladder
What is a malignant mass of the urinary bladder?
Rhabdomyosarcoma - homogenous mass adherent to bladder wall
Shape of the R adrenal vs L adrenal?
Rt - pyramid shaped
Lt - crescent shaped
How to determine a hemorrhage vs neuroblastoma?
Hemorrhage - will change and resolve
Neuroblastoma - will remain unchanged and grow larger
What stands for CAH?
Congenital Adrenal Hyperplasia
Female patient presents with virilism. Ultrasound shows enlarged adrenal glands with a cerebriform pattern. What is the most common diagnosis?
CAH
What is the most common adrenal tumour in childhood?
Neuroblastoma
Neuroblastoma’s are uncommon after what age?
8
What is the term for a mature neuroblastoma and considered less malignant?
Ganglioneuoma
SF of neuroblastoma?
- Echogenic mass with poorly defined borders
- Calcifications, hypoechoic areas of necrosis
- Displacement of the kidney (downward and outward)
What is known as a “functioning tumours originating in chromaffin tissue of the medulla”
Pheochromocytoma
Signs and symptoms of pheochromocytoma?
- Urinary catecholamine excretion (important in stress response)
- Hypertension
- Headaches
- Palpitations
- Diaphoresis
What muscle is a common location for hemorrhage, abscess or changes related to neoplasm?
Psoas
Where are retroperitoneal lymph nodes most commonly located near?
Ao/IVC
Enlargement of lymph nodes in the retroperitoneum are most commonly associated with? (3)
- Neuroblastoma
- Lymphoma
- Wilm’s tumour