Patologi Hepar, Pancreas, Bile duct Flashcards

1
Q

alur pembentukan bilirubin

A

hemoglobin - heme - biliverdin - bilirubin unconjugated - masuk hepar - ketemu ugt udp - bilirubin direk/conjugated - masuk empedu - sterkobilin urobilin

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2
Q

parameter anemia hemolitik

A

bilirubin unconjugated

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3
Q

parameter kerusakan hepar yang mengindikasikan injury/inflamasi

A

SGPT/ALT

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4
Q

penyebab tersering gangguan ekskresi ekstrahepatic

A

batu empedu

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5
Q

parameter cholestatis

A

peningkatan 5-nukleotide

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6
Q

gambaran kongesti kronik hepar

A

nutmeg liver

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7
Q

efek portal hypertension pada preumbilical

A

caput medusa

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8
Q

efek portal hypertension

A

hepatic ensefalopati, esofageal varises, caput medusa periumbilical, splenomegali, hemorrhoid

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9
Q

gambaran histopatologi pada hepatitis C

A

infiltrasi mononuklear, folikel limfoid, steatosis

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10
Q

karakteristik histopatologi hepatitis B

A

ground glass hepatocyte

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11
Q

hepatitis virus apa yang berperan hepatotoksik menimbulkan cedera secara tidak langsung

A

HBV

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12
Q

apa yang terjadi jika immune respon inadequate pada hepatitis akut

A

berubah menjadi kronik

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13
Q

hepatitis kronik aktif berkembang menjadi

A

sirrosis

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14
Q

histopatologi hepatitis akut

A

degenerasi balon hepatocyte

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15
Q

histopatologi hepatitis kronik

A

bridging nekrosis

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16
Q

clinical features sirrosis hepar

A

edema, ascites, haematemesis, spider nevi, gynecomastia, bleeding, infection, coma, ikterus

17
Q

manifestasi klinis yang terjadi pada sirrosis akibat dari rupturnya varises esofageal

A

haematemesis

18
Q

parameter pada HCC

A

naiknya AFP ALP

19
Q

5F kolesistitis kolelithiasis dkk

A

fair, fertile, female. fat, forty

20
Q

ikterik yang terjadi pada newborn

A

gangguan konjugasi bilirubin

21
Q

komplikasi paling awal sirosis hepatis

A

varises esofagus

22
Q

tahap akhir dari portal hypertension

A

ensefalopati hepatikum

23
Q

penanganan awal ruptur varises esofagus

A

rehidrasi/IV dengan kristaloid

24
Q

penyebab tersering sirosis hepatis di indo

A

HBV

25
Q

tanda yang sering ditemukan di abses hepar pyogenik

A

hepatomegali

26
Q

komplikasi abses hepar pyogenik yang paling fatal itu apa

A

ruptur ke peritoneum/pleura

27
Q

Pada cholestasis parameter yang meningkat

A

ALP dan 5-NT