Antiemetik Flashcards

1
Q

gejala yang muncul saat kemoreseptor Trigger Zone sudah tersensitisasi pada proses muntah?

A

mual, dilatasi pupil, hipersalivasi, pucat dingin, kontraksi duodenum dan abdomen, relaksasi LES

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2
Q

neurotransmitter utama di CTZ

A

dopamine

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3
Q

contoh obat golongan antihistamin

A

Promethazine, Cinnarizine, Dimenhydrinate, Diphenhydramine

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4
Q

indikasi penggunaan antihistamin

A

motion sickness, vertigo dan gangguan fungsi labirin

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5
Q

indikasi penggunaan promethazine

A

Motion sicknes, antialergi,

sedasi pre/post-operasi

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6
Q

side effect promethazine

A

Sedation, confusion,

disorientation

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7
Q

dosis penggunaan promethazine

A

12,5-25mg

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8
Q

indikasi penggunaan dimenhydrinate

A

motion sickness, menierre disease

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9
Q

dosis penggunaan dimenhydrinate

A

50-100mg

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10
Q

obat yang digunakan pada keluhan motion sickness

A

dimenhydrinate

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11
Q

farmakoterapi antimietik yang bisa memblokir H1 dan M1 sekaligus

A

cinnarizine

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12
Q

indikasi penggunaan cinnarizine

A

gangguan fungsi labirin, vertigo

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13
Q

efek samping cinnarizine

A

Drowsiness, Blurred vision

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14
Q

dosis penggunaan cinnarizine

A

12,5-50mg

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15
Q

farmako golongan antihistamin yang memiliki efek samping penurunan fungsi kognitif

A

dipenhydramine

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16
Q

efek samping dipenhydramine

A

Sedation
Confusion
decrease cognitive function

17
Q

indikasi penggunaan metoclorpramide

A

PNOV, GERD, drug-induced

nausea, migrain

18
Q

obat yang memiliki side effect dystonia

A

metorclorpramide

19
Q

dosis metoclorpramide

A

10-15 mg

20
Q

efek samping penggunaan metoclorpramide

A

Extrapiramidal dystonia,

sedation, and dry mouth

21
Q

farmako PNOV yang memiliki efek samping dry mouth

A

domperidone

22
Q

indikasi pengobatan farmako serotonin antagonis

A
  • Chemotherapy-Induced Nausea & Vomiting
  • Postoperative Nausea & Vomiting
  • Radiation-Induced Nausea & Vomiting
23
Q

farmako yang digunakan pada indikasi CINV dengan tipe low emetic risk

A

prochlorperazine, domperidone,metoclorpramide, dexamethasone

24
Q

dosis ondancetron pada PONV

A

8mg

25
Q

faktor pasien pada PONV

A

gender, obese, gangguan soistemik, uremia

26
Q

penyebab muntah pada ibu hamil

A

o Tonus sfingter gastroesofagus ↓
o Sekresi asam lambung ↓
o Pengosongan lambung lambat

27
Q

farmakoterapi yang paling aman untuk mengatasi emesis gravidarum

A

dimenhydrinate, dipenhydramine, metoclorpramide

28
Q

farmakoterapi yang paling tidak direkomendasikan untuk ibu hamil

A

prochlorperazine, promethazine