PATHOLOGY Flashcards
pathos
pain; suffering
divisions of pathology
- Gross and Microscopic
- Anatomic Pathology (biopsies)
- Clinical Pathology (CC, Hema, CM, etc)
frequent division to replace old cells; high turn over; e.g. blood cells and skin cells
labile cells
definite pattern of replication with cells lost by wear and tear being replaced by the mitotic activity of others; e.g. hepatocytes, renal tubular cells, mesenchymal cells
stable cells
non-replicating; e.g. cardiac and neurons
permanent cells
incomplete or defective tissue development; kidneys, gonads, adrenals
aplasia
non appearance of the organs
agenesia
failure of an organ to reach or achieve its full mature or adult size; did not mature
Hypoplasia (IMMATURE PO PLA-SIA) AHSFAHHA
failure of an organ to form an opening
atresia
shrinkage in the size of the cell by loss of cell substance (lumiliit kapag di ginagamit)
atrophy
decrease in size due to decreased work load
physiologic atrophy
decrease in size primarily due to denervation of muscle, diminished blood supply, nutritional deficiency, old age, disuse, some are idiopathic
pathologic atrophy
increase in the SIZE of cells; cells got LARGE; NO NEW ONES
Hypertrophy (LARGE TROPHY)
increase in the number of cells; cardiac and skeletal muscle does not undergo mitosis; BPH - Benign Prostate Hyperplasia
hyperplasia
compensatory; regeneration of liver following partial hepatectomy
physiologic hypertrophy
change of one cell type to another; reversible
metaplasia
most metaplasia in chronic smokers
columnar to squamous
metaplasia in Barret’s esophagus (long term GERD/acidic)
squamous to columnar
atypical hyperplasia
dysplasia
variation of size, shape, and orientation
dysplasia