HORMONAL CYTOLOGY Flashcards
produced by proliferating granulose theca cells of the ovarian follicles
estrogen
estrogen acts upon
superficial cells
- large; polyhedral flat cells
- cytoplasm; may be acidophilic or basophilic
- presence of small dark pyknotic nuclei
superficial cells (SUPER=LARGE)
- polyhedral or elongated
- cytoplasm: basophilic with vacuoles
- vesicular nuclei
- medium large
intermediate cells
BOAT shaped intermediate cells with a strong tendency to FOLD and CURL their edges
NAVIcular (BOAT=NAVY)
- expression of the combined estrogen-progesterone effect
- found in the latter half of menstrual cycle, during pregnancy, menopause
- may also be found as a result of abnormal androgen stimulation
Navicular cells
- round to oval shaped cell
- has a translucent basophilic cytoplasm
- double wall appearance
pregnancy cells
fried egg/sunny side up appearance
parabasal cells
found from 2 weeks of age to puberty, after childbirth, abortion or miscarriages, and after menopause
parabasal cells
round, slightly oval cells, with relatively large nucleus that occupying half or more of the cell volume
basal cells
found in vaginal smears ONLY BEFORE PREGNANCY and AFTER MENOPAUSE
basal cells
Cytohormonal Maturation Index
Parabasals:Intermediate:Superficials (PIS)
what is the highest during SHIFT TO THE RIGHT; ESTROGEN EFFECT; MENOPAUSAL WHO ARE TAKING ESTROGEN
Superficial (0/10/90)
- shift to the right kasi nasa right ‘yung S sa PIS
- increased ESTROGEN sa Superficial cells
shift to the MIDZONE; PROGESTERONE effect; during PREGNANCY
Intermediate cells (0/70/30)
- midzone nasa gitna I sa PIS
- increased progesterone sa Intermediate cells
shift to the LEFT; PRE-MENARCHE (hindi pa nireregla); PREMENOPAUSAL
Parabasal cells
- shift to the left - nasa left side P sa PIS