Pathologies Flashcards
Accessory Navicular
Extra navicular
Incorporated into tibialis posterior tendon
Possible pain and tenderness in area
Associated with pes planus, putting strain on tib post tendon, leading to inflammation
Also possible irritation from side of shoes
Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis AKA Lou Gehrig’s Disease
One of most common neuromuscular diseases, etiology unknown, not known to be autoimmune
Degeneration of upper and lower motor neurons
Unable to send messages to muscles which they control, which leads to atrophy
Nerves themselves degenerate, not myelin related (unlike MS)
LOSS of ability to control VOLUNTARY movement
Muscle Atrophy, Rapidly progressive weakness
Spasticity
Dysarthria (difficulty speaking)
Dysphagia (difficulty swallowing)
Dyspnea (difficulty breathing)
Cognitive function generally spared
Does not affect sensation
Steady decline, worsening symptoms
Fatal
Arthrogryposis
Congenital joint contractures
Rare 1 / 11 000 live births
Genetic/Environmental- intrauterine, decreased movement in womb
Abnormal fibrosis of the muscle tissue, causing shortening
Unable to perform passive extension/flexion in affected joints
Autonomic Dysreflexia
Sudden onset of excessively high blood pressure
Not treated promptly, may lead to seizures, strokes and death
Often occurs in spinal cord injured individuals with lesions above T6
Headache
Flushed face
Sweating
Slow heart rate
Reaction of autonomic (involuntary) nervous system to overstimulation (triggered by afferent stimuli), BP increases, HR slows and beomes irregular, BP cannot be restored to normal because of spinal cord damage
Causes Overfull bladder/bowel UTI Pressure sores Broken bones Tight clothing/DEVICES
Avascular Necrosis
Cellular death (necrosis) of BONE components due to interruption of blood supply
Without blood, bone tissue dies/collapses
If involves bones of a joint, often leads to destruction of joint articular surfaces
Blounts Disease
Growth disorder of the tibia
Causes lower leg to angle inward
AKA tibial bowing / vara
Can be rapidly progressive
Thought to be due to effects of weight on the growth plate
Inner part of the tibia just below the knee fails to develop normally, causing angulation of the bone
KAFO, or eventually surgery
Bunions/Bunionette
Hallux abducto valgus deformity
Lateral deviation of the great toe
Controversial etiology
Poorly fitting shoes, Genetic factors
Pressure applied to the side of the big toe, forces it inward toward and sometimes under or over the other toes
Bump is from swollen bursal sac or osseus anomaly, also part of the first met head tilted out
Tissue surrounding joint become swollen and tender
First met sesamoid bone may also become deviated
Orthotic splints
Toe spacers/separators
Orthotics (accommodative padding/shielding)
Surgery
Carpal Tunnel Syndrome (CTS)
Median entrapment neuropathy
Causes Paresthesia (tingling), Pain, Numbness
Palmar aspect of Thumb, index, middle, radial half of ring finger
Wrist pain
Sometimes through the night (seems to be aggravated when sleeping with flexed wrist)
Caused by crowding/irritation/compression of the median nerve within the carpal tunnel, thickening from irritated tendons or generalized swelling and irritation in the area can cause CTS
Carpal tunnel made up of carpal bones, 9 flexors tendons, connective tissue
Charcot Joint
AKA neuropathic arthropathy (joint disease)
Progressive degeneration of weight bearing joint
Bony destruction
Bony resorption
Joint Deformity
Decreased peripheral sensation, proprioception, fine motor control
Pathological process can result in
Ulceration
Superinfection
Loss of function
Amputation
Death
Underlying Mechanisms (2 theories)
Neurotrauma
- loss of peripheral sensation
- leads to progressive microtrauma to the joint
- damage goes unnoticed by patient
- resultant inflammatory resorption of traumatized bone renders region weak and susceptible to further trauma
- poor fine motor control generates unnatural pressure on certain joints
- leading to additional microtrauma
Neurovascular
- neuropathic patients have dysregulated autonomic nervous system
- desensitized joints receive significantly greater blood flow
- hyperemia leads to osteoclastic
Treatment
immobilization total contact cast
Pneumatic AFO
Surgical correction
Takes 6-9 months for edema/erythema to recede
Charcot Marie Tooth (CMT)
Hereditary Motor and Sensory Neuropathy, Demyelinating neuropathy
One of most common inherited neurological disorders affecting approx 1 / 2500
Characterized by
Progressive loss of muscle tissue
Touch sensation
Symptoms usually begin late childhood, early adulthood
Initial symptom is foot drop Claw toe/Pes Cavus Atrophy muscle tissue in legs Weakness in hands and forearms Loss of touch sensation Neuropathic pain
Possible respiratory/GI problems
Must avoid prolonged periods of immobility as it can accelerate symptoms of CMT
Mutations cause defects in neuronal proteins
Cause Demyelinating neuropathy
SCHWANN CELLS demyelinated, Myelin sheath may be damaged, may lead to axonal degeneration
Schwann/Myelin/Axon damage leads to poor nerve conduction
Chondromalacia Patella (CMP)
Inflammation of underside of the patella and cartilage softening
AKA patellofemoral pain syndrome
Condition may result from acute injury to the patella or chronic friction between the patella and groove in the femur through which it passes during knee flexion
Overuse, injury, neuromas, malignment, patellar maltracking etc.
can cause deterioration and break down of the cartilage
Cartilage no longer smooth, making movement painful
Club foot - Talipes Equinovarus
Congenital deformity involving one foot or both
Inversion of subtalar joint, complete hindfoot inversion
Adduction of forefoot at talonavicular joint and calcaneo cubiod joinit
Equinus and varus ankle
Supination of entire fotot
Plantarflexed
May appear to be walking on ankles, lateral sides of their feet
No single known cause, usually single isolated birth defect, associated with other birth defects such as spina bifida
Serial casting has shown to be effective
Followed by AFO orthosis to hold feet in plantargrade position
Denis Browne Bar, AFO, FO
Surgery usually not necessary however 2 are performed
Tenotomy- release of achilles tendon
Anterior tibial tendon transfer- tendon moved from first ray to the first ray to the third ray in order to release inward traction of foot
Compartment Syndrome
An acute (trauma) or chronic (repetitive activity) condition affecting an upper or lower extremity
Characterized by increased pressure within a muscle compartment causing severe pain
Swelling within compartment contained by fascia causes increased intracompartmental pressure
Compression of muscles, nerves and blood vessels within a closed space can lead to muscle, nerve and circulatory system damage
If left untreated, extensive tissue death can occur, amputation may be necessary
Can lead to volksmans contracture
Congenital Diaphragmatic Hernia (CDH)
Congenital malformation of the diaphragm
Most common type is Bochdalek hernia (95% of cases) - hole is posterolateral corner of diaphragm, allows passage of abdominal viscera into chest cavity
Malformation of diaphragm allows abdominal organs to push into the proper lung formation
Life threatening pathology in infants
Causes death due to 2 complications
Pulmonary hypolasia- incomplete development of the lungs
Pulmonary hypertension - excessively high blood pressure in pulmonary artery/vein
Associated with scoliosis
Depuytren’s Contracture
Fixed flexion contracture of the hand due to palmar fibromatosis (palmar fascia abnormally thick)
Inherited proliferative connective tissue disorder
Palmar fascia thickens and shortens so that tendons connected to fingers cannot move freely
Fingers bent toward the palm, cannot be fully extended
Decreased ability to grip objects
Usually painless
Ring and little finger most commonly affected, middle finger in more advanced cases, index and thumb usually spared
Contractures progress slowly
Table top test for diagnosis, hand on table, see if fingers touch the table
Dequervain’s Tenosynovitis
Pain inflammation of 2 tendons in the thumb (extensor pollicus brevis, abductor pollicus Longus)
Pain, swelling, tenderness over thumb side of the wrist and base of the thumb
Motion may be difficult and painful especially when pinching/grasping objects
Difficulty gripping
From Overuse, Repetitive Hand or wrist movement, or possibly trauma
Finkelstein Test
Make fist with thumb placed in palm
Wrist ulnarly deviated
Down’s Syndrome
Genetic disorder caused by presence of all or part of a third copy of chromosome 21
Most common chromosome abnormality in humans
Physical growth delays
Muscle hypotonia
Excessive joint laxity, atlanto-axial instability
Excessive space between large toe and second toe
Lateral Epicondylitis
AKA Tennis elbow
Painful condition of elbow caused by OVERUSE (racquet sports or other activity) or trauma
NON inflammatory, Degeneration of tendon’s attachment, weakening of anchor site, placing greater stress on area
Point of soreness/tenderness over lateral epicondyle
Pain from gripping movements of the wrist, especially wrist extension
Extensor muscles/tendons on lateral epicondyle of humerus damaged from overuse
Tendon usually involved is Extensor Carpi Radialis Brevis (ECRB)
Medial Epicondylitis
AKA golfer’s elbow, pitcher’s elbow
Overuse injury (or trauma) affecting flexor-pronator muscles originating on medial epicondyle
Repetitive flexing, gripping, swing, can cause microtears in tendons
Pain and inflammation of tendons
Femoral Anteversion/Retroversion
Anteversion - Inward twisting of the femur
Retroversion- Outward twisting of the femur
Often occurs symmetrically
In toeing gait, look to see if patella turned inward
Bow-legged appearance
Caused by position in uterus, genetic?
Normal child born with 40 degrees femoral anteversion
Gradually decreases to 10 to 15 degrees at adolescense
Guilian-Barre
Rare neurological disorder where body’s immune system attacks its own peripheral nerves
Often follows viral/bacterial infection
3 / 100 000, mostly age 30-50
Results in inflammation of the myelin and blockage of nerve conduction
Motor, sensory, autonomic nerve failure
Acute symptoms can take place over few hours or days
Muscle weakness/paralysis Difficultly breathing/swallowing Inability to move eyes Shortness of breath Sensation may be affected
Severity of nerve damage range greatly, most experience ascending symmetrical muscle weakness in lower and upper extremity
Following acute onset of condition, most patients gradually improve and recover, but some are left with life long disability
Orthoses to aid in weakness (most commonly drop foot), prevent contracture
Haglunds Deformity
Bony Enlargement at the back of the heel
Also swelling and redness at back of heel
Most often leads to painful bursitis (inflammation of fluid filled sac between tendon and bone)
Soft tissue near the Achilles tendon insertion becomes irritated when bony enlargement rubs against shoes
“pump bump”