Multiple Sclerosis

Question 1

Description

Answer 1

Inflammatory disease of the CNS

Characterized by demyelination

Question 2

Etiology

Answer 2

Uncertain

Genetic

Autoimmune

Environmental: geographic, vial

Question 3

General Stats

Answer 3

F: M 2.3 : 1

Average age of onset 30

3rd most common cause of disabling illness in persons between ages 15-50

Diagnosis: 2 attacks separated in time and space, MRI, CSF

Question 4

Disease course

Answer 4

Relapsing remitting 60%

Chronic progressive, primary or secondary 20%

Benign, occasional relapses 20%

Malignant, 5% of patients die within 5 years

Question 5

Movement impairments

Answer 5

Ataxia

Tremor

Spasticity

Paresis - weakness of voluntary movement

Plegia- paralysis

Question 6

Sensation impairments

Answer 6

Pain

Parasthesiae

Question 7

Other symptoms

Answer 7

Optic neuritis- inflammation of optic nerve, causing complete or partial loss of vision

Neurogenic bladder and bowel- dysfunction due to disease of CNS

Speech, cognition

Question 8

MS Treatment

Answer 8

Individualized

Steroids

Immunomodulators

Exercise

Energy conservation

Mobility aids: bracing, cane, scooter, wheelchair