Path review Flashcards
type of herniation that complesses the ant cerebral artery
subfalcine
type of herniation that gives blown pupil, hemiparesis, duret hemorrhages
transtentorial
type of herniation that can damage respiration and cardiac centers of brainstem
tonsillar
most common vascular site of embolism
MCA distribution
most common site of clot in brain
MCA and basilar arteries
red neurons occur in what time frame
12-24 hours
gliosis occurs in what time frame
14+ days
typical pt with AVM
young man with seizures
artherosclerotic aneurysm usually occurs where?
basilar aa
disease associated with berry aneurysms
adult polycystic kidney disease
duret hemorrages usually occur from
tearing of vessels during herniation
causes slit hemorrhages
hypertension
common sites of hypertensive hemorrhages
white matter, deep gray matter, cereballum
common cause of parenchymal hemorrage
Cerebral amyloid angiopathy
plaques formed of
beta amyloid
location of plaques
extracellular
tangles formed of
tau
tangles located
intracellular
first place in brain dementia starts to form
entorhinal cortex
protein in lewy bodies
alpha synuclein
clinical criteria for lewy body dementia
demantia within 1 year of parkinson sx
ALS destroys…
both upper and lower motor neurons
most common glaucoma
open angle
most acutely serious glaucoma
closed angle
glaucoma with iris stuck to cornea
closed angle
glaucoma with cup shaped optic nerve
closed angle
corneal degeneration with whote blue ring around the corneal region
acus senilis
cause of acrus senilis
increased cholesterol or scarring of cornea
cause of pterygium.pinuecula
sun damage causing submucosal elevation in the cinjunctiva
can cause saucer like depression of cornea
pinguecula
bad type of macular degeneration
wet
most common type of macular degeneration
dry
congential causes of cataracts
CMV, rubella
causes of adult cataracts
steroids, sun, diabetes
how diabetes causes blindness
diabetes leads to angiogenesis, leading to microaneurysms, which are leaky, leading to macular edema, leading to vessels developng over the optic nerve
common causes of retinal artery occlusion
Ophthalmology, thrombosis, emboli
vein occlision can lead to
neovascularization and closed angle glaucoma
most common eye tumor
melanoma
histology of eye melanoma
spindled and epitheloid cells
adverse features of melanoma
epitheloid histology
mutation in retinoblastoma
RB (13q14) (needs 2 hits)
chalazion is a chronic..
stye (blocked eyelid gland)
type of myositis that is shows in adults
dermato
dermatomyositis in adults could be manifestation of
paraneoplastic syndrome
most common inflamatory myopathy in elderly
inclusion body myopathy
vaculoses in imflamatory myopathy contain
tau and beta
myopathy that does NOT respond to steroids
inclusion body
worse kind of MD
duchene’s
pseudohypertropy of calves indicates
DMD
CSF findings in MS
oligoclonal banding
headache, lethargy, coma a few weeks after an infection
acute demyelinating encephalomyelitis
caused by JC virus
progressive multifocal leukoencephalopathy
people who get progressive multifocal leukoencephalopathy are usually
immunocompromised
signs of progressive multifocal leukoencephalopathy
ring enhancing lesions, viral inclusions in oligodendrocytes
of weirnacke/korsakoff: the irreversiable serious one
korsakoff
non alcoholic causes of Wernickie-korsakoff
chronic gastritis or profound vomiting
wernicke lesions
mamillary bodies
korsakoff lesions
thalmus
cause of ataxia and nystagmus in alchoholics
cerebellar atrophy
sx of b12 deficency
ataxia, numbness/tingling, spastic weakness, paraplegia