Path: MS system Flashcards

1
Q

Osteitis deformans aka? S/S? Lab?

A

pagets
older males, mosaic layers, bowing tibia, IVORY WHITE VERTEBRA, pseudofractures,
Lab: increased alkaline phosphatase 40 times higher

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2
Q

Neurofibromatosis aka?

A

von recklinghausens disease
genetic
coast of maine café au lait spots
can compress nerves

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3
Q

fibrous dysplasia is?

A

bone thinning, lesions, growth in bone.
monostotic= one bone
polyostsotic= many bones

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4
Q

mccune-albrights disease

A

found in young girls, several bones involved, endocrine related

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5
Q

hemangioma

A

MC benign bone tumor of the vertebra

affects only one level

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6
Q

osteochondroma

A

MC benign bone tumor of the body
sessile- no stalk
peduncle- stalk

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7
Q

osteogensis imperfecta

A
brittle bone disease
genetic
abnormal collagen
fractures
BLUE sclera
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8
Q

OsteopEtrosis

A

overgrowth & sclerosis bone, however is weak & fractures

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9
Q

osetopOrosis

A

post menopausal
increases fractures
Dowager hump

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10
Q

osteomyelitis

A

Staph infection in bone

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11
Q

Potts disease

A

TB of the spine
spreads lungs> thoracics> eats the joints> vertebra collapses> inc. kyphosis
causes Gibbus deformity

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12
Q

Avulsion fracture

A

ligament pulls away part of bone

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13
Q

comminuted fracture

A

has many fragments

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14
Q

Compound fracture

A

protrusion through the skin

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15
Q

simple fracture

A

no protrusion through the skin

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16
Q

avascular necrosis

A

aka AVN, ischemic necrosis, aseptic necrosis, osteochondrosis

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17
Q

Osgood schlatter’s

A

tibial tuberosity AVN, 13-16 y/o

18
Q

leg calve perthes

A

femoral head AVN, 4-8 y/o

19
Q

Osteoathritis

A
aka DJD, degenerative joint disease
narrowing joint spaces
subchondral sclerosis
osteobalstic activity
-asymmetrical
-repetitive- response to stress
-weight bearing joints
20
Q

rheumatoid arthritis

A
females 20-40 autoimmune
symmetrical
pannus formation
ulnar deviation
inflammation of synovium
affects limbs & cervicals
morning stiffness
21
Q

Fettys syndrome

A

long standing RA, hepatomegaly, splenomegaly

22
Q

juvenile RA

A

stills disease

23
Q

Labs RA

A

RA latex

sero +

24
Q

Caplans

A

RA + pneumonia

25
Q

Reiters

A
reactive arthritis
adult male; STD, chlamydia
feet & spine conjunctivitis
urethritis & arthritis (heel Spur)
"lovers heal"- calcaneal spur
"cant see, cant pee, cant dance with me"
26
Q

Charcot joint

A
aka neurogenic joint
6 D's
debris
dysfunction
deformity
dislocation
destructive
distention
disease
posterior column destruction, diabetes mellitus (feet), syringomyelia (shoulder)
27
Q

psoriatic

A
ray sign- pencil in cup deformity in phalanx
destroys joint- mouse ears
70% skin
30% arthritis
-silver scales
- pitted nails
28
Q

Gout

A

-initially starts inside the joint
- attacks small joints
MC big toe - podagra
tophi
destruction around the joint
purine metabolism problem
uric acid crystal build up

29
Q

pseudogout aka CPPD

A

big joints
knee
calcium pyrophosphate crystals

30
Q

ankylosing spondylitis

A
aka Marie strumpell
symmetrical- loves the pelvis- starts in SI joints
young males, poker or bamboo spine
makes the spine rigid
HLA-B27
sero -
breathing difficulties
trolley track, dagger sign, shiny corner
31
Q

DISH- Diffuse idiopathic skeletal hyperostosis

A
aka Forestiers disease
over 50 y/o
all CALCIFICATION
cervical pain
stiffness, dec. ROM
affects cervical
assoc with diabetes
Facets are not fused
32
Q

Erb-duchennes MD

A
0-12 boys
autosomal recessive
severe-fatal
pseudohypertrophy of calf muscles
increased CPK 300 times
x-linked
gower sign
33
Q

Becker MD

A

10-70 y/o
autosomal recessive
mild
pelvis & legs

34
Q

fascioscapulohumeral dystrophy

A

10-20 y/o
autosomal DOMinant
mild
face & shoulders

35
Q

Guillain-Barre

A

acute polyneuropathy
polyradiculuitis
following surgery or immunization
ASCENDING paralysis

36
Q

Myasthenia gravis

A
female
myoneural junction
decrease  Ach  receptors especially the cranial nerves
ptosis
diplopia
eyes are effected first
37
Q

lambert eaton

A

inhibit Ca++
older women
common with small cell carcinoma
increased contractions with repeated stimuli

38
Q

Charcot-marie-tooth

A

autosomal disease
onset in childhood
horrible calf pain- calf muscle atrophy
demyelination

39
Q

Ehlers- Danlos syndrome

A

autosomal dominant
hyperextensible skin & joints
large artery
fragile

40
Q

McArdles

A
30-40 year old
myalgia
early fatigue
painful cramps
weakness of excercising muscles