Path: MS system Flashcards
Osteitis deformans aka? S/S? Lab?
pagets
older males, mosaic layers, bowing tibia, IVORY WHITE VERTEBRA, pseudofractures,
Lab: increased alkaline phosphatase 40 times higher
Neurofibromatosis aka?
von recklinghausens disease
genetic
coast of maine café au lait spots
can compress nerves
fibrous dysplasia is?
bone thinning, lesions, growth in bone.
monostotic= one bone
polyostsotic= many bones
mccune-albrights disease
found in young girls, several bones involved, endocrine related
hemangioma
MC benign bone tumor of the vertebra
affects only one level
osteochondroma
MC benign bone tumor of the body
sessile- no stalk
peduncle- stalk
osteogensis imperfecta
brittle bone disease genetic abnormal collagen fractures BLUE sclera
OsteopEtrosis
overgrowth & sclerosis bone, however is weak & fractures
osetopOrosis
post menopausal
increases fractures
Dowager hump
osteomyelitis
Staph infection in bone
Potts disease
TB of the spine
spreads lungs> thoracics> eats the joints> vertebra collapses> inc. kyphosis
causes Gibbus deformity
Avulsion fracture
ligament pulls away part of bone
comminuted fracture
has many fragments
Compound fracture
protrusion through the skin
simple fracture
no protrusion through the skin
avascular necrosis
aka AVN, ischemic necrosis, aseptic necrosis, osteochondrosis
Osgood schlatter’s
tibial tuberosity AVN, 13-16 y/o
leg calve perthes
femoral head AVN, 4-8 y/o
Osteoathritis
aka DJD, degenerative joint disease narrowing joint spaces subchondral sclerosis osteobalstic activity -asymmetrical -repetitive- response to stress -weight bearing joints
rheumatoid arthritis
females 20-40 autoimmune symmetrical pannus formation ulnar deviation inflammation of synovium affects limbs & cervicals morning stiffness
Fettys syndrome
long standing RA, hepatomegaly, splenomegaly
juvenile RA
stills disease
Labs RA
RA latex
sero +
Caplans
RA + pneumonia
Reiters
reactive arthritis adult male; STD, chlamydia feet & spine conjunctivitis urethritis & arthritis (heel Spur) "lovers heal"- calcaneal spur "cant see, cant pee, cant dance with me"
Charcot joint
aka neurogenic joint 6 D's debris dysfunction deformity dislocation destructive distention disease posterior column destruction, diabetes mellitus (feet), syringomyelia (shoulder)
psoriatic
ray sign- pencil in cup deformity in phalanx destroys joint- mouse ears 70% skin 30% arthritis -silver scales - pitted nails
Gout
-initially starts inside the joint
- attacks small joints
MC big toe - podagra
tophi
destruction around the joint
purine metabolism problem
uric acid crystal build up
pseudogout aka CPPD
big joints
knee
calcium pyrophosphate crystals
ankylosing spondylitis
aka Marie strumpell symmetrical- loves the pelvis- starts in SI joints young males, poker or bamboo spine makes the spine rigid HLA-B27 sero - breathing difficulties trolley track, dagger sign, shiny corner
DISH- Diffuse idiopathic skeletal hyperostosis
aka Forestiers disease over 50 y/o all CALCIFICATION cervical pain stiffness, dec. ROM affects cervical assoc with diabetes Facets are not fused
Erb-duchennes MD
0-12 boys autosomal recessive severe-fatal pseudohypertrophy of calf muscles increased CPK 300 times x-linked gower sign
Becker MD
10-70 y/o
autosomal recessive
mild
pelvis & legs
fascioscapulohumeral dystrophy
10-20 y/o
autosomal DOMinant
mild
face & shoulders
Guillain-Barre
acute polyneuropathy
polyradiculuitis
following surgery or immunization
ASCENDING paralysis
Myasthenia gravis
female myoneural junction decrease Ach receptors especially the cranial nerves ptosis diplopia eyes are effected first
lambert eaton
inhibit Ca++
older women
common with small cell carcinoma
increased contractions with repeated stimuli
Charcot-marie-tooth
autosomal disease
onset in childhood
horrible calf pain- calf muscle atrophy
demyelination
Ehlers- Danlos syndrome
autosomal dominant
hyperextensible skin & joints
large artery
fragile
McArdles
30-40 year old myalgia early fatigue painful cramps weakness of excercising muscles
