Path) Autopsy

Question 1

What are some benefits of autopsies

Answer 1

—

Question 2

When is a medical certificate of cause of death Issued
What are some mandatory reasons to refer to the coroner?
Coroner’s autopsy — what is ascertained

Answer 2

—

Question 3

Cause of death — how would it be explained

Answer 3

Mechanism vs cause

1a (thing/event that caused death) due to 1b
2 other significant conditions but not related to direct cause

Question 4

History taking for post mortem — what do you need to know

Random— what does granular surface on the kidneys imply

Answer 4

—-

Chronic sclerosis — long standing hypertension

Question 5

Atherosclerosis on histology specimen — what can you see

Answer 5

Cholesterol, calcification, small louden

Cholesterol clefts

Fatty streaks

Question 6

What is the physiology of plaque formation in endothelial vessels

Answer 6

Vascula wall —> endothelial damage

Then FOAM cells and other try and repair

Forms plaque

Inflammatory scarring process

Pre clinical then clinical

Question 7

Fatty streaks in vessels — what are these and what can hapen

Answer 7

Endothelial damage — some improve but some become ulcerated lesion in severe atherosclerosis.

Question 8

Image — thrombus formation / rupture on histology

Post MI, what would you see on left ventricle histology

What else may you see after

Answer 8

Ischaemia, acute inflammatory process — neutrophils BLUE

And heavy granulation tissue forms over time

Question 9

What does coagulative necrosis, oedema and neutrophils
Then also inflammation
Then also granulomatous tissue look like

Also when does this happen

Answer 9

—