I&I) How Viruses Cause Disease Flashcards
What is virus made of
What is the journey of a virus
How can virus get into body - pto for prompt
Skin, alimentary tract, urogenital, eye
What is apical and basolateral viral release
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How can virus enter the blood.
What is the presence of virus in blood called
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Viruses and neural spread
How cab this happen? Pto for promt - what happens here
What is neurotropic, neuroinvasivem neurovirulent
GIVE EG
Tissue tropism
What is this. What can determine this. Pto for promt
Cell receptors?
Cellular proteins? What can they regulate
Cell protease? - eg?
What makes a virus virulent?
—4 points if ya can
How can viruses injure cells? There are THREE ways
Cytolyic, non cytolytic, free radicals
Give examples of viruses and what their route of transmission would be
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What are some types of infectio?
For chronic/persisting, what is happening with immune system
Latent infection
What kinds of viruses present with these and how do they work, what happens what do you see
Examples of this
What could happen
How does the host response vary between acute and chronic infection
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How can viruses evade immune system?? Pto for hints, give examples
Antigenic variation
Inhibition of antigenic processing
Production of cytokines receptor homologues
Production of immunosuppressive cytokines
Infection of immunocompetant
What can viruses to to inhibit antigen processing? Examples?
How can IL-10 help viruses evade immune system?
What else
How are IL-1 and IFN-gamma and IN10 involved too
Examples for all please
What is the structure of influenza virus type a
NA - neuroaminidase
HA - hemagglutinin
How can influenza viruses ecade host defence mechanisms? Pto
What is the difference between antigenic shift and drift