Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharma > Parkinson > Flashcards

Parkinson Flashcards

0
Q

Dopamin-

Rezeptoragonisten

A

Nicht-Ergoline:
Pramipexol

Ergoline (2. Wahl)
Cabergolin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Biosynthetische Vorstufevon Dopamin

A

Levodopa (immer Komb. mit Benserazid oder mit Carbidopa)
Gleichzeitige Gabe von Benserazid oder Carbidopa, um unerwünschte periphere Decarboxylierung von L-Dopa zu hemmen. Decaboxylasehemmstoff(peripher)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

MAOb-Hemmstoffe

A

Selegilin
Rasagelin
Hemmung des zentralnervösen Dopamin- (und Katecholamin‑)Abbaus → Verlängerung der Dopaminwirkung → L-Dopa-Bedarf↓

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

COMT-Hemmstoffe

A

Entacapon, nur in Komb. mit Levodopa/Carbidopa
oder Levodopa/Benserazid
Hemmung der Catechol-O-Methyltransferase (COMT) → Dopamin-Abbau↓ → Dopaminwirkung↑ → L-Dopa-Bedarf↓

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

NMDA-Rezeptorantagonisten

A

Amantadin

Antagonismus am Glutamat- (bzw. NMDA‑)Rezeptor → Dopaminerge Wirkung!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Muskarinrezeptor-Antagonisten

A

Biperiden

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Pharma (41 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions