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Topnotch Pharmacology (Sept 2017) > Pancreatic Drugs > Flashcards

Pancreatic Drugs Flashcards

1
Q

Somogyi

A

When evening dose of insulin is high

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2
Q

When evening dose of intermediate insulin is low

A

Waning

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3
Q

Phenomenon due to growth hormone spike

A

Dawm phenomenon

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4
Q

Most physiologic strategy for insulin therapy

A

Basal bolus

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5
Q

1st gen sulfonylurea

A

Chlorpropamide

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6
Q

May cause disulfiram rxn

A

Chlorpropamide

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7
Q

2nd gen sulfonylurea

A

Glipizide

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8
Q

CI in patients with hepatic impairment and renal insufficiency

A

Glipizide (2nd gen)

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9
Q

A meglitinide

A

Repaglinide

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10
Q

Increases insulin secretion from pancreatic B cells by closing ATP sensitive K channels

A

Secretagogued

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11
Q

Activates AMP stimulated and protein kinase leading to inhibition of hepatic and renal gluceneogenesis

A

Biguanides

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12
Q

Increase target tissue sensitvity to insulin by activating the peroxisome proliferator activated receptor gama nuclear receptor

A

Thiazolidinediones

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13
Q

Inhibit a glucosidase enzyme

A

Alpha glucosidase inhibitors

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14
Q

Example of aloha glucosidase inhibitor

A

Acarbose

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15
Q

Amylin analog

A

Pramlintide

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16
Q

Incretin modulator

A

Exanatide

17
Q

DPP4 inhibitor

A

Sitagliptin

18
Q

Inhibits GI and pancreatic lipases; reduces absorption of fats

A

Orlistat

19
Q

Inhibits NE and Serotonin reuptake in the cns

A

Sibutramine

20
Q

Selectively blocks cannabinoid(CB 1 receptors

A

Rimonabant

21
Q

Anti obestiy drug with SE of suicidality

A

Rimonabant

22
Q

For severe hypoglycemia and beta blocker overdose

A

Glucagon

23
Q

Recombinant parathyroid hormone

A

Teriparatide

24
Q

Active vitamin d

A

Calcitrol

25
Q

Used for secondary hyperparathyroidism in CKD

A

Calcitrol

26
Q

Inhibits bone resorption therefore decreasing serum calcium and phosphate

A

Calcitonin

27
Q

Used for paget disease

A

Calcitonin

28
Q

Supresses activity of osteoclasts. Inhibits bone resoprtion

A

Alendronate

29
Q

Example of bisphosphonate

A

Alendroanate

30
Q

A phosphate binding resin

A

Sevelamer

31
Q

May mask signs of hypoglycemia

A

Beta blockers

Topnotch Pharmacology (Sept 2017) (38 decks)

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