Antimalarial Flashcards
1
Q
Prevents polymerization of heme into hemozoin
A
Chloroquine
2
Q
Complexes with dna to prevent strand separation. Blocks dna replication and transcription
A
Quinine
3
Q
Antimalarial doc for pregnant women
A
Mefloquine
4
Q
Forms electron transport-transferring redox compounds that act as cellular oxidants.
A
Primaquine
5
Q
Disrupts mitochondrial electron transport.
A
Atovaquone
6
Q
Long acting folate antagonist
A
Pyrimethamine
7
Q
Impairs progrny of malarial apicoplastic genes resulting in abnormal cell division
A
Doxycycline
8
Q
Antimalarial with significant cardiotoxic side effect
A
Halofantrine
9
Q
Forms toxic free radicals in malarial food vacuole
A
Artemsinin
