Antibitoics Flashcards

1
Q

May cause red man syndrome

A

Vancomycin

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2
Q

Peptide antibiotic that interferes with a late stage in cell wall synthesis in gram positive organism

A

Bacitracin

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3
Q

Antimetabolite, blocks incorporation of D ala into pentapeptise side chain of peptidoglycan

A

Cycloserine

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4
Q

May cause aplastic anemia and gray baby syndrome

A

Chloramphenicol

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5
Q

DOC for rickettsiae

A

Tetracycline

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6
Q

May cause tooth enamel dysplasia/discoloration

A

Tetracycline

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7
Q

Tetracycline should not be taken with

A

Milk

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8
Q

Only macrolide that does not inhibit CYP450

A

Azithromycin

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9
Q

Cross resistance b/n clindamycin and wc drug is commkn

A

Macrolide

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10
Q

Binds to 50s subunit. BACTERICIDAL

A

Quinupristin- dalfopristin

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11
Q

Basis for once daily aminoglycoside dosing

A

Post antibiotic effect

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12
Q

Has narrowest therapeutic window among aminoglycosides

A

Amikacin

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13
Q

Aminoglycoside used for endocarditis

A

Gentamicin

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14
Q

Aminoglycoside used for multi drug resistant TB

A

Amikacin

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15
Q

SE is nephrotoxicitu, ototoxicity and NM blockade

A

Aminoglycoside

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16
Q

Aminoglycoside used for brucellosis, tularemia, brucellosis

A

Streptomycin

17
Q

Aminoglycoside that may cause congenital deafness

A

Streptomycin

18
Q

Aminoglycoside used for skin infections, bowel prep for elective surgery, Hepatic enceph

A

Neomycin

19
Q

Neomycin induced NM blockade may be reverse by

A

Calcium gluconate and neostigmine

20
Q

Aminoglycoside used for drug resistant gonorrhea

A

Spectinomycin

21
Q

Inhibits bacterial cell wall synthesis by binding to D Ala D ala terminus of nascent peptidoglycan

A

Vancomycin