Antibitoics Flashcards
May cause red man syndrome
Vancomycin
Peptide antibiotic that interferes with a late stage in cell wall synthesis in gram positive organism
Bacitracin
Antimetabolite, blocks incorporation of D ala into pentapeptise side chain of peptidoglycan
Cycloserine
May cause aplastic anemia and gray baby syndrome
Chloramphenicol
DOC for rickettsiae
Tetracycline
May cause tooth enamel dysplasia/discoloration
Tetracycline
Tetracycline should not be taken with
Milk
Only macrolide that does not inhibit CYP450
Azithromycin
Cross resistance b/n clindamycin and wc drug is commkn
Macrolide
Binds to 50s subunit. BACTERICIDAL
Quinupristin- dalfopristin
Basis for once daily aminoglycoside dosing
Post antibiotic effect
Has narrowest therapeutic window among aminoglycosides
Amikacin
Aminoglycoside used for endocarditis
Gentamicin
Aminoglycoside used for multi drug resistant TB
Amikacin
SE is nephrotoxicitu, ototoxicity and NM blockade
Aminoglycoside