Pain III Flashcards

1
Q

What are the 2 componenents of pain

A

sensory-discriminative and emotional

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2
Q

How is prefrontal cortex involved in pain

A

cognitive aspects of pain percieved here

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3
Q

what role does anterior cingulate cortex have in pain

A

paying attention to pain

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4
Q

what roles does amygdala have in pain

A

fear, assign negative contex tto pain

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5
Q

how is hippocampus associated with pain

A

memory o fpain

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6
Q

insula

A

relay station to the limbic system and to the hypothalamus

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7
Q

when is anterior cingulate cortex active

A

perception of pain
imagining pain
observation of pain in others

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8
Q

when does gating mechanism close

A

in response to normal stimulation of fast conductivity large nerve fibers (a-beta)

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9
Q

when does gating mechanism open

A

slow conduction pain fibers (A delta and C fibers)

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10
Q

C fiber affect on inhibitory interneurons

A

inhibit inhibitory interneurons

activate secondary afferents

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11
Q

A bea affect on inhibiotry interneurons

A

activate inhibitory interneurons

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12
Q

What happens when C fibers inhibit inhibitory interneurons

A

activation of secondary afferents and transmissino of pain signal

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13
Q

what happens when A beta fibers acitivate inhibitory internerous

A

inhibition of secondary afferent and transmission of pain signaal

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14
Q

compeition between A beta and C fibers work to do what

A

decrease initial pain response

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15
Q

Sites of action for pain

A

periaquductal gray
rostral ventral medulla
locus-coerulues

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16
Q

how is pain moducated in periaquductral gray

A

activate enkephalin-releasing neurons that project to raphe nuclei in brainstem

17
Q

what is analgesia in ventralateral PAG blocked by

A

naloxone

18
Q

response to pain modulation in ventrolateral PAG

A

analgesia
decrease bp and HR
vasodilation of skeletal muscle and viscera
immobility

19
Q

hwo does ventrolateral pain modulcation affect ANS

A

sympathetic inhibition

20
Q

response to pain modulation in dorsal PG

A
decrease bp
increase hr
vasocontristion of skin and versia
increase muscle tone
aversive behavior
21
Q

how does dorsal pain modulation affect ANS

A

sympathetic excitation

22
Q

what are common pain types

A

chronic
referred
projected
neuropathic

23
Q

reflective (referred) pain

A

percieved at location other than site of painful stimulus

24
Q

convergence

A

somatic and viscersal pain fibers on secondary afferents in dorsal horn

25
Q

projeced pain provides evidence to support wah tthroy

A

labeled line theory of sensory processing

26
Q

what does phantom pain occur due to

A

neuroplasticity and reorganization

27
Q

caudalagia

A

continuous burning pain long after seemingly trivial injuries

28
Q

how do you treat reflex sympathetic dystrophy

A

sympathetic or sympathetic nerve block