Pain Flashcards
Types of pain:
- nociceptive
- neuropathic
Nociceptive pain:
- somatic
- visceral
What does somatic pain feel like?
- well-defined
- aching
What does visceral pain feel like?
- diffuse
- deep
- squeezing
- usually whole hand approach
Neuropathic pain is indicative of…
damage/disease affecting the nervous system
What does neuropathic pain feel like?
- burning
- tingling
- electrical
- stabbing
- pins and needles
For acute pain, you can…
anticipate pain resolution
For chronic pain, you can’t…
anticipate pain resolution
Chronic pain can impact…
- use of medications
- monitoring
- counseling
- long term side effects
Indications for OTC analgesics:
- aches and pains
- fever reducer
- sore throat
- headaches
- toothaches
- muscular aches
- minor pain of arthritis
Adult OTC maximum dose for acetaminophen:
3 g
Adult monitored maximum dose for acetaminophen:
4 g
Acetaminophen is the leading cause of…
acute liver failure in the US
Risk factors for liver failure include…
- combination acetaminophen in products
- alcohol ingestion
- repeat dosing in excess of acetaminophen
OTC medications account for _____ ED visits among children under 12
1/3
T/F: FDA issues a safety alert for acetaminophen
T
What was the safety alert for acetaminophen about?
potentially fatal skin reaction such as:
- Stevens-Johnson syndrome
- toxic epidermal necrolysis
- acute generalized exanthematous pustulosis (AGEP)
For acetaminophen, there are potential fatal skin reactions w/…
any dose at any time
- rash
- blistering
- detachment of upper skin
Counseling points for acetaminophen for adults:
- avoid concurrent use of alcohol
- liver damage w/ overuse and/or alcohol abuse
- caution w/ combination products
- don’t need food
Onset of action for acetaminophen:
< 1 hr
Duration of action of acetaminophen:
4-6 hr or 8 hr
Counseling points for acetaminophen for pediatrics:
- avoid combination products
- can start right away
Salicylates are also known as…
aspirin
Max daily dose of salicylates:
4 g (10 tab/day)
T/F: you should give children salicylates
F
Salicylates can cause…
Reyes syndrome
Reyes syndrome is associated w/…
previous viral illness, influenza, cold, or chicken pox
T/F: Reyes syndrome is contagious
F
Reyes syndrome:
- fat accumulation in the liver and encephalitis
- death within few hours to days
Signs of Reyes syndrome:
- vomiting
- signs of brain dysfunction
- personality changes
- disorientation
- coma
Side effects of salicylates:
- GI upset
- bleeding (dose related)
- ringing in ears
Salicylates have drug interactions w/…
- warfarin
- antiplatelet (Plavix)
- NSAIDs/steroids
Contraindications for salicylates:
- salicylates sensitivity/allergies
- GI ulcers
- alcohol ( >3 drinks/day)
- pregnancy
- elderly ( > 325 mg/day)
- pediatrics
Higher the dose of salicylates, the higher risk of…
side effects
Salicylates can help prevent strokes by…
inhibiting prostaglandin synthesis and platelet aggregation
Dosage for salicylates and stroke prevention:
81 mg - 325 mg PO QD
Drug interactions for salicylates and stroke prevention:
NSAID and Asipirin
- take NSAID 30-120 min after / 8 hrs before aspirin
NSAIDs include…
- ibuprofen
- ketorolac
- meloxicam
- indomethacin
- etodolac
- nambutone
Adult dose for ibuprofen:
200-400 mg Q4-6 H prn
Max adult dose for ibuprofen:
1.2 g/day or < 2.4 g per physician
Child dose for ibuprofen:
- weight (preferred) and age based dosing
- can be repeated 6-8 hr prn w/ max of 4 doses per day
When do you refer children to physician after use of ibuprofen?
- fever/pain lasts > 3 days
- no improvement in 24 hrs
Side effects for ibuprofen:
- GI upset
- fluid retention/edema
- dizziness
- bleeding
Interactions w/ ibuprofen:
- warfarin
- lithium
- methotrexate
- alcohol
- NSAIDs/steroids
Precautions of ibuprofen:
- NSAID allergy
- cardiovascular disease
- pregnancy
- GI ulcers/bleeding
- geriatric
- undiagnosed migraines
One should discontinue ibuprofen if…
- fever lasts > 3 days
- pain > 10 days
- alcohol use is >3 drinks/day
200 mg of Naproxen base is the same as…
220 mg naproxen sodium
Adult dosage for naproxen:
200 mg Q8-12 H
- can take as much as 400 mg for initial dose
- take with food
Max dosage of naproxen per day:
600 mg