Oxygenation Flashcards
Alterations in respiratory function:
hypoventilation
hyperventilation
hypoxia
Hypoventilation:
Alveolar ventilation is inadequate to meet the oxygen demand of the body or eliminate sufficient carbon dioxide
Atelectasis is
a collapse of the alveoli, prevents normal exchange of oxygen and carbon dioxide
Hypoxia is
inadequate tissue oxygenation at the CELLULAR level.
Results from a deficiency in oxygen delivery or oxygen use at the cellular level
life threatening
Hypoxemia is
suboptimal normal partial pressure of oxygen.
Untreated hypoxemia will result in hypoxia.
Hypoxemia is common cause of hypoxia however hypoxia can exist without hypoxemia
Causes of Hypoxemia
Poor alveolar ventilation due to decreased tidal volume or respiratory rate
Decreased diffusion of oxygen from alveoli to pulmonary capillaries as a result of THICKENING of the alveolar-capillary membrane ventilation/perfusion mismatch
Shunting- occurs when venous blood travels from the right to left side of heart without passing by inflated alveoli resulting in MIXING of venous and arterial blood
Ventilation/perfusion mismatch
Causes of Hypoxia:
Anemic hypoxia
Ischemic stagnant hypoxia
Histotoxic hypoxia/dysoxia
Anemic hypoxia:
decreased ability to transport oxygen and can be result of low hemoglobin levels (anemia, hypovolemic shock) or reduced function of hemoglobin (carbon monoxide poisoning)
Ischemic/stagnant hypoxia:
occurs when there is decreased delivery of oxygen to tissue cells as a result of insufficient blood flow and which may be the result of systemic conditions (cardiac failure) or local disruption to circulation (tissue edema or local arterial damage).
Histotoxic hypoxia:
occurs when tissues are unable to properly utilize oxygen despite adequate oxygen supply and which occurs as a result of cellular poisons (cyanide), abnormal tissue oxygen requirements, or poor oxygen diffusion across cell membrane (tissue edema)
Hypoxemia ranges:
pO2 of less than 60 mmHG or an oxygen saturation of less than 90% leaving oxygen saturations in the range of 90-95%
Respiratory failure is defined as a
pO2 less than 50 mmHg and a pCO2 greater than 50 mmHG
Ventilation:
process of moving gases into and out of the lungs
Atelectasis:
collapse of the alveoli that prevents normal exchange of oxygen and carbon dioxide
External respiration:
exchange of O2 and CO2 between alveoli and blood
Gas transport:
blood transports O2 and CO2 to body cells
Internal respiration
exchange of O2 and CO2 between blood and cells
Blood and tissue oxygenation is through the process of ___________ (3)
Ventilation
Perfusion
Diffusion
Accumulation of carbonic acid in the body leads to
respiratory acid-base disorder termed respiratory acidosis
Majority of CARBON DIOXIDE molecules are transported in the blood as
BICARBONATE HCO2
Factors affecting respiration could stem from
integrity of the airway system (ventilation)
functioning cardiovascular system (perfusion)
functioning alveoli (diffusion)
functioning medulla & chemoreceptors
Physiologic factors Gas-exchange:
decrease oxygen-carrying capacity
hypovolemia
decrease inspired oxygen concentration
increased metabolic rate
Physiologic factors affecting gas-exchange:
Lung elasticity/compliance (ability to stretch and recoil)
Airway obstruction
musculature condition
trauma
neuromuscular disease
central nervous system
influences of chronic disease
Alteration in cardiac function that could affect oxygenation:
cardiac arrhythmias
congestive heart failure
valvular dysfunction
cardiac ischemia
Fick’s law of Diffusion
rate of a diffusion of gas is dependent on surface area and thickness of membrane
Factors affecting oxygenation
Developmental factors (age)
infants/toddlers
school age children and adolescents
young-middle age adults
older adults
medication
respiratory history
occupation
Psycho-social factors affecting oxygenation
environment
stress
emotions
health
Lifestyle factors: nutrition exercise smoking substance abuse
Afterload
resistance to left ventricular ejection
Angina pectoris
transient imbalance between myocardial oxygen supply and demand
results in aching, sharp, tingling or burning chest pain
Atelectasis
collapse of the alveoli that prevents normal exchange of oxygen and carbon dioxide
Bronchoscopy
procedure that allows viewing of airway through a thin viewing instrument called a bronchoscope.
During a bronchoscopy, your doctor will examine your throat, larynx , trachea , and lower airways.
Cardiac index
assessment of patient’s cardiac output based on size
Cardiac output
amount of blood ejected from the left ventricle each minute
normal: 4-6 L/min
increases during exercise, pregnancy, fever and decreases during sleep
Cardiopulmonary rehabilitation
helps patients achieve and maintain an optimal level of health through controlled physical exercise
nutrition counseling
relaxation and stress management techniques
prescribed medications and oxygen
cardiopulmonary resuscitation
CAB
Chest compression
Airway
Breathing
ventilation is done after first cycle of 30 chest compressions
Chest physiotherapy
group of therapies for mobilizing pulmonary secretions
include postural drainage, chest percussion and vibration
CPT is followed by productive coughing or suctioning of a patient who has decreased ability to cough
Chest tube
a catheter inserted through the thorax to remove air and fluids from the pleural space to prevent air or fluid from reentering the pleural space or to reestablish normal intrapleural and intrapulmonic pressures
common after chest surgery and chest trauma
used for treatment of pneumothorax or hemothorax to promote lung reexpansion