Fluid/Electrolytes Flashcards
Extracellular fluid (ECF)
fluid outside the cell
1/3 of body’s H20
more prone to loss
3 types
3 types of extracellular fluid:
Interstitial: fluid around/between cells
Intravascular: (plasma) fluid in blood vessels
Transcellular- CSF, synovial fluid, etc
Intracellular fluid (ICF)
Fluid inside the cell
Most 2/3 of body’s H20 is in the ICF
Infant fluid compartments:
60% of H20 is found in the ECF
40% of H20 is found in ICF
Adults or infants are more prone to fluid loss?
Infants!
Body tries to maintain homeostasis of fluids and electrolytes by regulating:
volumes
solute charge and osmotic load
What is the minimum output her hour necessary to maintain renal function?
30mL/hr
Loss of 10% body fluid= ______-weight loss and is _____
8% weight loss and is SERIOUS
Loss of 20% body fluid = _____ weight loss and is _____
15% weight loss and is FATAL
Electrolytes:
charged particiles
cations- positively charged ions
Na+, K+, Ca++, H+
Anions: negatively charged ions
Cl-, HCO3-, PO43-
Non electrolytes:
uncharged particles- proteins, urea, glucose, O2, CO2
Functions of body fluid (6)
medium for transport
cellular metabolism
solvent for electrolytes and other constituents
body temperature
digestion and elimination
lubricant
Hypothalamus:
thirst receptors
osmoreceptors monitor serum osmolarity.
If it rises, thirst mechanism is triggered
Sodium is found in the
extracellular compartment
Potassium is found in the
intracellular compartment
Magnesium is found more in the
intracellular compartment
Chloride is found in the
extracellular compartment
Solute homeostasis is maintained by
ion transport
water movement
kidney function
these functions act to keep body fluids:
electrically neutral
osmotically stable
Diffusion
movement of particles DOWN a concentration gradient
Facilitated diffusion
addition of specific carrier molecules to aid/accelerate diffusion (glucose transport into cell facilitated by insulin)
Osmosis
diffusion of water across a selectively permeable membrane
Active transport
movement of particles UP a concentration gradient; REQUIRES ENERGY
Osmolarity (tonicity)
concentration of particles in a solution
the greater the concentration (osmolarity) of a solution, the greater the pulling force (osmotic pressure)
A solution that has a HIGH osmolarity is a _____ solution
HYPERTONIC solution
A solution that has a LOW osmolarity is a _____ solution
HYPOTONIC solution
A solution that has EQUAL osmolarity is a ________ solution
ISOTONIC (normal saline)
Hypertonic fluids have a _____ concentration of particles (high osmolality) than ICF
higher!
Higher osmotic pressure shifts fluid from the cells into the
ECF
Cells placed in a hypertonic solution will
SHRINK!!!!!!
Hypertonic solution is used to
temporarily treat hypovolemia
expand vascular volume
fosters normal BP and good urinary output (often used post op)
Hypotonic fluids have less concentration of particles than
ICF
The low osmotic pressure shifts fluid from
ECF into cells
Cells placed in a hypotonic solution will
SWELL!
Hypotonic solution is used to
dilute plasma particularly in hypernatremia
treats cellular dehydration
do not use for patients with increased ICP risk or third spacing risk- edema!
Isotonic fluids have the same concentration of particles (osmolality) as
ICF
Osmotic pressure is therefore the _____ inside and outside the ____
SAME
cell
Cells do not ___ or ____ in an isotonic solution. They _____
DO NOT SWELL OR SHRINK
THEY STAY THE SAME!
Isotonic solution expands…
both intracellular and extracellular volume
used commonly for excessive vomiting and diarrhea
0.9% normal saline
D5W
Ringer’s Lactate
Albumin is a
serum protein that has osmotic properties called colloid pressure
Albumin pulls…
H2O from the interstitial compartments into the intravascular compartments (serum)
Helps to maintain BP
persons with low serum albumin levels tend to
retain fluid in their interstitial layers
What are abnormal assessments might you find in the client with low serum albumin levels?
EDEMA
HYPOTENSION
Third spacing is
when tissue injury occurs, proteins pathologically leak from the intravascular space into the interstitial space
Fluid volume deficit FVD (Hypovolemia)
Loss of both H20 and electrolytes from ECF
Causes of FVD (Hypovolemia)
Increased output
hemorrhage
vomiting
diarrgea
burns
OR
fluid shift out of vascular space (“third spacing”) into interstitial spaces
Isotonic dehydration:
H20 and electrolyte loss in equal amounts; diarrhea and vomiting
Hypertonic dehydration:
H20 loss is greater than electrolyte loss
excessive perspiration
diabetes
Assessment of fluid volume deficit Cardiovascular
Diminished peripheral pulses; quality 1+
decreased BP and orthostatic hypotension
Increased HR
Flat neck and hand veins in dependent position
Elevated Hematocrit (HCT)
Assessment of fluid volume deficit Gastrointestinal
Thirst
Decreased motility
diminished bowel sounds
possible constipation
Nursing diagnosis deficient fluid volume:
R/T loss of GI fluids via vomiting
AEB elevated Hct, dry mucous membranes, decreased output, thirst
Interventions for deficient fluid volume (hypovolemia)
prevent further fluid loss
oral rehydration therapy
IV therapy
Medications- antiemetics, antidiarrheals
Monitor VS, resp, renal, GI status
Monitor electrolytes- possible supplement Rx
Monitor weight and I/O
Hypervolemia:
excess fluid volume in the intravascular area
fluid overload is an excess of body fluid: over hydration
Excess fluid volume in interstitial spaces:
edema
Electrolyte functions:
work with fluids to keep the body in balance
regulate water distribution
muscle contraction
nerve impulse transmission
blood clotting
regulate enzyme reactions (ATP)
Regulate acid-base balance
Electrolytes are ___
solutes that are found in various concentrations and measured in milliequivalent units
anions or cations- homeostasis body needs total body anions-total body cations
Electrolyte imbalance of Potassium (K+)
Hypokalemia
Hyperkalemia
Electrolyte imbalance of Calcium (Ca2+)
Hypo/Hyper calcemia
Electrolyte imbalance of Magnesium (Mg2++)
Hypo/Hyper magnesia
Sodium normal range:
135-145mEq/L
Sodium facts!
MAJOR CATION
Chief electrolyte of the ECF
regulates volume of body fluids
Needed for nerve impulse & muscle fiber transmission (Na/K pump)
regulated by kidneys/hormones
Hyponatremia range:
Serum Na_ < 135mEq/L
Hyponatremia facts!
Results from excess of water or loss of Na+
Water shifts from ECF into cells
S/S: abd cramps, confusion, N/V
Tx: Diet/IV therapy/fluid restrictions
What are some medical conditions that may cause a dilution hyponatremia?
CHF
Renal failure
SIADH (cancer, pituitary trauma)
Addisons Disease (hypoaldosteronism & Na loss)
What are some conditions that might cause actual loss of sodium from the body?
GI losses- nasogastric suctioning, vomiting, diarrhea
Certain diuretic therapies
Permanent neurological damage can occur when serum Na levels fall below 110 mEq/L. Why?
Hypotonic environment swells cells, increasing ICP- brain damage
Hypernatremia range:
Serum Na+>145mEq/L
Hypernatremia facts
Results from Na+ gained in excess of H2O OR Water is lost in excess of Na+
water shifts from cells to ECF
Hypernatremia signs and symptoms:
thirst
dry mucous membranes & lips
oliguria
increased temp & pulse
flushed skin
confusion
Treatment for hypernatremia
IV therapy/diet
Potassum:
3.5-5.0 mEq/L
Chief electrolyte of ICF
Major mineral in all cellular fluids
Potassium aids in
muscle contraction
nerve/electrical impulse conduction
regulates enzyme activity
regulates IC h20 content
assists in acid-base balance
Potassium is regulated by
kidneys/hormones
inversely proportional to Na
ECF has which two major divisions? minor division?
Intravascular- liquid part of blood (plasma)
interstitial- between cells and outside blood vessels
Transcellular (minor)- cerebrospinal, pleural, peritoneal, synovial fluids are secreted by epithelial cells
Major cations in body
Sodium (Na+)
Potassium (K+)
Calcium (Ca2+)
Magnesium (Mg2+)`
Major anions in body
Chloride (Cl-)
Bicarbonate (HCO3-)
Osmolality
measure of the number of particles per kilogram of water. `
Isotonic
fluid with the same tonicity as normal blood
Hypotonic
solution is more DILUTE than the blood
Cell will swell
Hypertonic
solution is MORE CONCENTRATED than normal blood
cell SHRINKS
Processes that move water and electrolytes between body compartments
active transport
diffusion
osmosis
filtration
Active transport:
cells maintain their high intracellular electrolyte concentration by active transport
requires energy in form of ATP to move electrolytes across cell membrane AGAINST concentration gradient
(low concentration to high concentration)
Sodium-potassium pump
Diffusion
Passive movement of electrolytes DOWN a concentration gradient
higher concentration to lower concentration
requires proteins that serve as ion channels
Osmosis
water moves across cell membranes by osmosis.
water moves through a membrane that separates fluids with different particle concentrations
Osmotic pressure
an inward pulling force caused by particles in the fluid
Hydrostatic pressure
force of the fluid pressing outward against a surface
Blood colloid osmotic pressure (oncotic pressure)
is an inward-pulling force caused by blood proteins that helps move fluid from the interstitial area back into capillaries)
Fluid homeostasis includes which three processes
fluid intake and absorption
fluid distribution
fluid output
Fluid output normally occurs through which 4 organs
skin, lungs, GI tract, kidneys
Insensible water loss is
NOT VISIBLE
CONTINOUS through the skin and lungs
Approximately how many L of fluids moves into the GI tract daily and returns to the ______
3-6 L daily
Returns to ECF
ADH regulates the ____
Antidiuretic hormone
osmolality of the body fluids by influencing how much water is excreted in urine
ADH is released by
Posterior pituitary gland
More ADH is released if
body fluids become more concentrated
Factors that increase ADH levels include
severely decreased blood volume (dehydration, hemorrhage)
pain
stressors
some medications
ADH causes
renal cells to RESORB water, taking water from the renal tubular fluid and putting it BACK INTO BLOOD
ADH levels decrease if
body fluids become TOO DILUTE
This allows more water to be excreted in urine
The RAAS regulates
ECF volume by influencing how much sodium and water are excreted in urine