oxazolidinones Flashcards
1
Q
mechansm
A
bind to 23s rRNA of the 50s subunit
2
Q
spectrum
A
gram (+) MRSA, VRE, coagul (-), strep.
3
Q
is there resistance
A
rare
4
Q
place in tehrapy
A
VRE
alternative to vancomycin
5
Q
when do we avoid using these
A
bactermia/endocarditis
6
Q
SE
A
bone marrow suppression after 2 wks.
periopheral neuropathy
7
Q
drug interactiosn
A
MOAi possible serotonin syndrome