Outcome 13 Nephrology and Genitourinary Flashcards
t or f. acute glomerulonephritis is both a primary or secondary disorder
t
most common form of acute glomerulonephritis
secondary
acute glomerulonephritis usually follows this type of infection
group B streptococcal infection
result of chronic glomerulonephritis is the progressive destruction of the glomeruli and eventually ____
end-stage renal disease (ESRD)
crystals of urea on the skin that result from the body trying to excrete urea through the sweat glands
uremic frost
arteriovenous fistula access
*
types of peritoneal dialysis
*
uses gravity to aid dialysate solution in filtering process, thereby draining waste into a bag worn around waist
continuous ambulatory peritoneal dialysis (CAPD)
uses a machine that continuously cycles the dialysate and extracts the waste
continuous cycling peritoneal dialysis (CCPD)
typically performed at night while patient sleeps
ccpd
75% of kidney transplants are performed on patients with these 3 things
- diabetic renal failure
- hypertensive renal disease
- glomerulonephritis
part of glomerulus affected by nephrotic syndrome
basement membrane
nephrotic syndrome can follow these 4 hings
- glomerulonephritis
- exposure to certain toxins or drugs
- pregnancy
- kidney transplant
3 main causes of acute renal failure
- diminished blood flow to the kidney
- intrarenal damage or disease
- mechanical obstruction of urine flow
CRF results from the gradual and progressive loss of this kidney component
nephrons
CRF is reversible
f
2 dietary substances that should be restricted in patients with CRF
- protein
2. sodium
areas of kidney inflamed in pyelonephritis
renal pelvis and connective tissues
normal cause of pyelonephritis
infection ascending from the lower urinary tract
other 2 common causes of pyelonephritis
- pregnancy
2. renal calculi
part of the kidney dilated in hydronephrosis
renal pelvis
cause of hydronephrosis: obstruction of urine flow due to these 4 factors
- renal calculi
- tumors
- inflammation
- pregnancy
excessive amounts of 2 substances in the blood leading to the formation of renal calculi
- calcium
2. uric acid
large stone formed in the shape of the renal pelvis
staghorn calculus
cystitis and urethritis are common forms of this type of infection
lower utis
name for the diabetes-associated renal changes that comprise diabetic nephropathy
glomerulosclerosis
diabetic nepehropathy can be expected with this type of diabetes
type 1
normal renal tissue is replaced with this type of tissue in polycystic kidney disease
multiple grapelike cysts (causes gross enlargement of the kidney
form appears during infancy or childhood
autosomal recessive
form appears during middle age
autosomal dominant
acquired form of polycystic kidney disease is
long term kidney disease or dialysis
cause of neurogenic bladder
insult to brain, spinal cord, or nerves supplying the lower urinary tract
uncontrollable leakage of urine from the bladder during activities
stress incontinence
types of activities that can cause stress incontinence
physical exertion or actions that stress the pelvic muscle (laughing, sneezing, coughing, lifting, stretching, running)
causes of stress incontinence
weakening of the pelvic floor muscles and urethral stricture from childbirth, pregnancy and menopause, obesity and certain medicatons
Inflammation and swelling of the glomeruli of the kidneys
acute glomerulonephritis
t or f. acute glomerulonephritis can be primary or secondary to a systemic disease
t
acute glomerulonephritis usually follows a ____ of throat or skin
streptococcal bacterial infection
acute glomerulonephritis is marked by these 3 things
- proteinuria
- edema
- decreased urine volume
acute glomerulonephritis is caused by group A and B ____
hemolytic streptococcus.
acute glomerulonephritis can also result from an immune reaction that causes circulating ____ to be trapped within the ____
antigen-antibody complexes; capillaries and glomerulus
3 tests for acute glomerulonephritis that reveal bilateral enlargement of the kidneys
- high blood urea nitrogen levels
- elevated ESR
- kidney ureter bladder (KUB)
Slowly progressive noninfectious disease that can lead to irreversible renal damage and renal failure.
chronic glomerulonephritis (CGN)
advanced stage of chronic glomerulonephritis (CGN) results in inflammation followed by the progressive destruction of ____
glomeruli
in chronic glomerulonephritis (CGN), ____ lodged in the ____ trigger an inflammatory response and glomerular injury
antigen antibody complexes; glomerular capsular membrane
treatment for chronic glomerulonephritis (CGN) aims to prevent these 2 conditions
- CHF
2. uremia
Disease of the basement membrane of the glomerulus
nephrotic syndrome
another term for nephrotic syndrome
nephrosis
Nephrotic syndrome is also sometimes referred to as ____
protein losing kidney
nephrotic syndrome is caused by increased ____ of the glomerulus meaning renal damage
permeability
3 conditions that can lead to nephrosis
- DM
- infections
- allergic reactions
in nephrosis, dietary intake of protein is adjusted to ___
GFR
sudden severe function in renal function
acute renal failure (ARF)
acute renal failure (ARF) is a common clinical emergency because ____ begin to accumulate in blood causing an acute ____
nitrogenous waste; uremic episode
acute renal failure (ARF) is caused by diminished ____ to the kidney and ____ to urine flow
blood flow; mechanical obstructions
treatment of ARF aims to reduce _____ damage
permanent kidney
gradual progressive loss of nephrons with irreversible loss of renal function and gradual onset uremia
chronic renal failure (CRF)
3 conditions that cause chronic renal failure (CRF)
- glomerulonephritis
- pyelonephritis
- polycystic kidneys
chronic renal failure (CRF) is often the end stage of chronic ____
renal disease; obstruction of urine flow
condition that can occur with chronic renal failure (CRF)
severe anemia
inflammation of renal pelvis and connective tissue of one or both kidneys
pyelonephritis
pyelonephritis is caused by this bacteria that ascend from the lower urinary tract to the kidneys
e.coli
drug to treat pyelonephritis
penicillin flouroquinolones
abnormal dilation of the renal pelvis caused by pressure from urine that can’t flow past an obstruction in the urinary tract
hydronephrosis
pyelonephritis is caused by a buildup of pressure in the kidneys because of an ____
obstruction
surgical removal of the obstruction to treat hydronephrosis; when surgery isn’t an option, a ____ may be inserted
nephrostomy tube
medical term for kidney stones
renal calculi
renal calculi is caused by an excessive amount of ___ or ___
calcium; uric acid
4 risk factors for renal calculi
- prolonged dehydration
- prolonged immobilization
- urinary stasis from obstruction
- crystalline inhibitors
2 main treatments for renal calculi
- extracorporeal shockwave lithotripsy
2. electrohydraulic lithotripsy
Inflammation of the urinary bladder and urethritis, inflammation of the urethra most common form of lower UTI
infectious cystitis and urethritis
4 causes of infectious cystitis and urethritis
- e. coli
- klebsiella
- enterobacter
- proteus pseudomonas
renal changes from diabetes mellitus
diabetic nephropathy
term for the changes from DM
glomerulosclerosis
diabetic nephropathy occurs when lesions of the glomeruli eventually cause ____ to decrease
filtration rate
diabetic nephropathy may also be caused by insufficient control of ____ and ____
blood glucose levels; blood pressure
grape-like cyst replaces normal renal tissue
polycystic kidney disease (PKD)
t or f. polycystic kidney disease (PKD) is inherited but may not manifest until adolescence/adulthood
t
acquired polycystic kidney disease (PKD) is a sequela of ____ and/or _____
long term kidney disease; long term dialysis
recessive polycystic kidney disease (PKD) appears in ____
infants and children
dominant polycystic kidney disease (PKD) appears in ____
middle aged individuals
2 treatment options for polycystic kidney disease (PKD)
- dialysis
2. kidney transplant
in polycystic kidney disease (PKD), there may be surgical removal of kidneys because of these 3 factors
- pain
- stones
- persistent infection
dysfunction of the urinary bladder that consists of difficulty in emptying the bladder or urinary incontinence
neurogenic bladder
neurogenic bladder results in insult to these 3 areas
- brain
- spinal cord
- other nerves supplying the lower urinary tract
treatment for neurogenic bladder aims to prevent ___
UTIs
neurogenic bladder is also treated by providing a means of storing urine and emptying the bladder
catheterization
uncontrolled leakage of urine from the urinary bladder during physical exertion or actions that stress the pelvic muscles (laughing, sneezing, coughing, etc)
stress incontinence
stress incontinence is caused by weakening of these 2 areas
- pelvic floor muscles
2. urethral structure
3 treatments for stress incontinence
- kegel exercises
- endoscopy
- voiding cystourethrogram