Other mental health drugs Flashcards
Lithium carbonate
CLASSIFICATION =
Mood stabiliser
USE=
Bipolar disorder, manic episodes, depressive episodes
MODE OF ACTION =
Unknown.
ADVERSE =
drowsy, tremor, cold, dry mouth, nausea
Carbamazepine
CLASSIFICATION =
Mood stabiliser
Anticonvulsant
USE=
Bipolar disorder, manic episodes, Temporal lobe epilepsy
MODE OF ACTION =
Stabilises voltage-gated sodium channels, to limit opening, and also potentiates GABA receptors.
ADVERSE =
Dizzy, nausea, drowsy
Sodium valproate
CLASSIFICATION =
Mood stabiliser, anticonvulsant
USE=
Bipolar disorder, manic episodes
‘Petit mal’ epilepsy
MODE OF ACTION =
Unknown
Anticonvulsant action caused by blockade of voltage-dependant sodium channels and increased levels of GABA in brain
ADVERSE =
headache, weight gain, nausea
Triazolam,
Midazolam,
Lorazepam
CLASSIFICATION = Anxiolytic hypnotic sedative benzodiazepine
USE=
Anxiety, sleep problems, muscle relaxant (Cerebral palsy AND MS).
MODE OF ACTION =
Acts receptors in CNS to increase power of inhibitory action of GABA
ADVERSE =
withdrawal symp, memory loss, sedation
Diazepam,
Clonazepam
CLASSIFICATION =
Anxiolytic, hypnotic, sedative, benzodiazepine, anticonvulsant
USE=
Anxiety, sleep problems, epilepsy, CS , MS
MODE OF ACTION =
Acts receptors in CNS to increase power of inhibitory action of GABA
ADVERSE =
memory loss, sedation
Zopiclone
CLASSIFICATION =
Anxiolytic, hypnotic, sedative, non-benzodiazepine, cyclopyrrolone
USE=
Anxiety, sleep problems, muscle relax
MODE OF ACTION =
Acts receptors in CNS to increase power of inhibitory action of GABA
ADVERSE =
nausea, drowsy , dry mouth
Phenytoin
CLASSIFICATION =
Anticonvulsant , antiepileptic
CNS depressant
USE=
Epilepsy, seizure
MODE OF ACTION =
suppress deep attachments of cortical neurons, affect movement sodIum ions across M
ADVERSE =
bleeding gums, liver damage, headache, GI upset
Lamotrigine
CLASSIFICATION =
Anticonvulsant, antiepileptic, mood stabliser
USE=
Epilpesy, seizure, bipolar depressive episodes.
MODE OF ACTION =
affect move of sodium ion across membrane, reduces release of glutamate
ADVERSE =
nausea, dizzy, back pain , insomnia
Vigabatrin
CLASSIFICATION =
Anticonvulsant, antiepileptic, CNS depressant
USE=
epilepsy, seizure
MODE OF ACTION =
inhibits enzyme which degrades GABA
ADVERSE =
depression , confusion , weight gain
Gabapentin
CLASSIFICATION =
Anti convulsant , antiepileptic, cns depressant
USE=
partial seizures, neuropathic pain
MODE OF ACTION =
unknown
ADVERSE = dizzy, weak , breast swelling,