Antinausea

Question 1

Metoclopramide, Phenothiazine

Answer 1

Anti-nausea, antiemetic,
- vomiting caused by delayed gastric emptying , infection

blocks the D2 receptors in the chemoreceptor trigger zone.
- sedation , diarrhoea,

Question 2

Promethazine, Cyclizine

Answer 2

Anti-nausea, antiemetic , antihistamine
-motion sickness, vertigo

binds to H1 receptor in vomitng and vestibular centres, blocks histamine from binding and inhibit or reduce vomiting
- sedation

Question 3

Hyoscine, Atropine

Answer 3

Anti-nausea, antiemetic , anticholinergic
- motion sickness, premedication

blocks cholinergic receptors to prevent GI response
- dilated pupils, dry mouth , tachy

Question 4

Ondansetron

Answer 4

Anti-nausea, antiemetic
- Vomiting and nausea induced by chemotherapeutic drugs

blocks serotonin receptors
- constipation, headaches,