anticoagulant

Question 1

heparin , dalteparin

Answer 1

anticoagulant
- treatment of = DVT, clotting disorders etc

binds to enzyme antithrombin III, causing inactivation of thrombin
- risk of haemorrhage, bleeding, pain at injection site

Question 2

warfarin

Answer 2

anticoagulant
prevention and treatment of
- DVT, embolism , AF

interferes with the use of vitamin K for prothrombin production
- risk haemorrhage

antidote - vitamin K

Question 3

davigatran

Answer 3

anticoagulant
prevention and treatment of
DVT, stroke, AF, pulmonary embolism

directly inhibits thrombin , stops conversion of fibrinogen to fibrin
- gi upset, increase risk of MI, renal impairment

Question 4

clopidogrel

Answer 4

antiplatelel
- PVD, prevention - MI and stroke

inhibits, adp receptor on platelet cell membranes, causing inactivation
- brusising, GI upsets

Question 5

streptokinase

Answer 5

anticoagulant
DVT

dissolves existing clots by converting of plasminogen into plasmin , prevents further clotting
- risk of bleeding