Antibiotic

Question 1

penicillin
amoxicillin
flucloxacillin

Answer 1

antibiotic (chemotherapeutic)
- bacterial infection 
spectrum 
Penicillin – narrow 
Amoxicillin – broad
Flucloxacillin - narrow

contains a β-lactam ring , inhibits peptidoglycan formation in bacterial cell wall. causing water to enter cell making it burst.
- GI upset, headache, opportunist infection (thrush)

Question 2

augmentin

Answer 2

Chemotherapeutic, antibiotic
- bacterial infection - broad

contains amoxicillin +clavulanic acid, inhibits β-lacatamase to prolong antibiotic action
- allergy, rash , diarrhoea

Question 3

cefaclor

Answer 3

chemotherapeutic , antibiotic
- bacterial infections - broad

contains a β-lactam ring , inhibits peptidoglycan formation in bacterial cell wall. causing water to enter cell making it burst.
- gi upset, muscle pain , superinfection

Question 4

gentamicin , neomycin

Answer 4

antibiotic (chemotherapeutic)
bacterial - broad

causes misreading of mRNA by ribosome to cause abnormal protein structure.
- gi issues, toxicities.

Question 5

erthromycin

clarithromycin

Answer 5

antibiotic (chemotherapeutic)
bacterial - broadbacterial - broad

affects the function of larger microbial ribosomal subunit, affects protein synthesis of microorganism
- gi issues, superinfections

Question 6

norfloxacin, ciprofloxacin

Answer 6

antibiotic (chemotherapeutic)
bacterial - broad (UTIS)

inhibits DNA synthesis of bacteria, retarding growth.
- rash , headache

Question 7

teracycline, doxycycline

Answer 7

antibiotic (chemotherapeutic)
bacterial - broad spectrum

binds to smaller ribosomal subunit, interfers with protein synthesis of microorganism.
- deformity/discolouration of growing teeth and bones.