Oral Path Exam 3 - Soft Tissue Masses Part 3

Question 1

What lesion?

Caused by ectopic sebaceous glands

Answer 1

Fordyce granules

Question 2

What lesion?

Present in over 80% of the population

Answer 2

Fordyce granules

Question 3

What lesion?

Multiple yellow-white papules

Answer 3

Fordyce granules

Question 4

What lesion?

Most commonly found on the buccal mucosa and vermilion of the upper lip

Answer 4

Fordyce granules

Question 5

What lesions? (3)

Diagnosed by biopsy

Answer 5

Fordyce granules
Gingival cyst of the adult
Epidermoid cyst

Question 6

What lesion?

No tx necessary (variation of normal)

Answer 6

Fordyce granules

Question 7

What lesion?

Caused by superficial dilated and tortuous veins

Answer 7

Varix/varicosities

Question 8

What lesion?

Weakening of blood vessel walls and loss of tone in supporting CT

Answer 8

Varix/varicosities

Question 9

What lesion?

Rare in children
Occurs in 2/3rds of people over age 60

Answer 9

Varix/varicosities

Question 10

What lesion?

Blue-purple nodules, may be solitary or multiple

Answer 10

Varix/varicosities

Question 11

What lesion?

Common on ventral and lateral surfaces of the tongue, lips, and buccal mucosa

Answer 11

Varix/varicosities

Question 12

What lesion?

Can become thrombosed (firm, forms a clot)

Answer 12

Varix/varicosities

Question 13

What lesion?

Usually a clinical diagnosis can be made, but a biopsy for solitary lesions found on the lip and buccal mucosa may be indicated

Answer 13

Varix/varicosities

Question 14

What lesion?

No tx necessary

Answer 14

Varix/varicosities

Question 15

What lesion?

Derived from rests of dental lamina

Answer 15

Gingival cyst of the adult

Question 16

What lesion?

Soft tissue counterpart to lateral periodontal cyst

Answer 16

Gingival cyst of the adult

Question 17

What lesion?

Found in adults

Answer 17

Gingival cyst of the adult

Question 18

What lesion?

Painless, dome-like swellings that are bluish-gray in color

Answer 18

Gingival cyst of the adult

Question 19

What lesion?

May cause “cupping out” of alveolar bone

Answer 19

Gingival cyst of the adult

Question 20

What lesion?

Predilection for mandibular canine and premolar area

Answer 20

Gingival cyst of the adult

Question 21

What lesion?

Always on facial gingiva/alveolar mucosa

Answer 21

Gingival cyst of the adult

Question 22

What lesions? (2)

Tx = excisional biopsy

Answer 22

Gingival cyst of the adult
Epidermoid cyst

Question 23

What other lesion causes a “cupping” defect of
underlying bone?

a. Pyogenic granuloma
b. Peripheral ossifying fibroma
c. Peripheral giant cell granuloma
d. Fibroma

Answer 23

c. Peripheral giant cell granuloma

Question 24

What lesion?

Keratin-filled cyst arising from hair follicle

Answer 24

Epidermoid cyst

Question 25

What lesion? Unusual before puberty

Answer 25

Epidermoid cyst

Question 26

What lesion? Nodular, fluctuant subcutaneous lesion

Answer 26

Epidermoid cyst

Question 27

What lesion? White or yellow (can be red if inflamed)

Answer 27

Epidermoid cyst

Question 28

What lesion? Common in acne-prone areas of head, neck, and back

Answer 28

Epidermoid cyst

Question 29

What lesion? NOT found intraorally

Answer 29

Epidermoid cyst

Question 30

What lesion? Caused by occlusion and dilation of a crypt of lymphoid tissue

Answer 30

Lymphoepithelial cyst

Question 31

What lesion? Most common in young adults

Answer 31

Lymphoepithelial cyst

Question 32

What lesion? Small submucosal mass that is white or yellow

Answer 32

Lymphoepithelial cyst

Question 33

What lesion? Firm or soft to palpation

Answer 33

Lymphoepithelial cyst

Question 34

What lesion? Commonly found on: Floor of mouth Ventral tongue Posterior lateral border of tongue Palatine tonsil Soft palate

Answer 34

Lymphoepithelial cyst

Question 35

What lesion? Diagnosed clinically or by biopsy

Answer 35

Lymphoepithelial cyst

Question 36

What lesion? Tx = do nothing or excisional biopsy

Answer 36

Lymphoepithelial cyst

Question 37

Which of the following is considered a variation of normal? a. Lymphoepithelial cyst b. Fordyce granules c. Varix d. Hemangioma

Answer 37

b. Fordyce granules

Question 38

What lesion? Caused by ectopic thyroid tissue

Answer 38

Lingual thyroid

Question 39

What lesion? Failure of thyroid bud to descend normally into neck

Answer 39

Lingual thyroid

Question 40

What lesion? More common in females

Answer 40

Lingual thyroid

Question 41

What lesion? Nodular mass on posterior dorsal tongue

Answer 41

Lingual thyroid

Question 42

What lesion? May be accompanied by dysphagia, dysphonia, and dyspnea

Answer 42

Lingual thyroid

Question 43

What lesion? 72% are accompanied by hypothyroidism

Answer 43

Lingual thyroid

Question 44

What lesion? Diagnosed by thyroid scan

Answer 44

Lingual thyroid

Question 45

What lesion? Avoid biopsy!! (due to risk of hemorrhage, and may be pt's only functioning thyroid tissue)

Answer 45

Lingual thyroid

Question 46

What lesion? Tx = follow-up and hormone therapy if necessary (may reduce size of symptomatic lesions)

Answer 46

Lingual thyroid

Question 47

Which of the following is found ONLY on the skin? a. Epidermoid cyst b. Kaposi sarcoma c. Lymphoepithelial cyst d. Fordyce granules

Answer 47

a. Epidermoid cyst

Question 48

What lesion? RET gene mutation

Answer 48

Multiple endocrine neoplasia type 2B (MEN2B)

Question 49

What lesions? Autosomal dominant inheritance pattern

Answer 49

Multiple endocrine neoplasia type 2B (MEN2B) Neurofibromatosis type 1 (NF1)

Question 50

What lesion? Mucosal neuromas are often the first sign

Answer 50

Multiple endocrine neoplasia type 2B (MEN2B)

Question 51

What lesion? Mucosal neuromas tend to involve oral cavity and are soft, painless papules/nodules

Answer 51

Multiple endocrine neoplasia type 2B (MEN2B)

Question 52

What lesion? Mucosal neuromas primarily seen on lips and anterior tongue but can also be seen on buccal mucosa, gingiva, and palate

Answer 52

Multiple endocrine neoplasia type 2B (MEN2B)

Question 53

What lesion has the following clinical presentation? Mucosal neuromas Medullary thyroid carcinoma Pheochromocytoma (adrenal gland tumor)

Answer 53

Multiple endocrine neoplasia type 2B (MEN2B)

Question 54

What lesion? Diagnosed by biopsy of oral lesions and genetic testing

Answer 54

Multiple endocrine neoplasia type 2B (MEN2B)

Question 55

What lesion? Tx = preventative thyroidectomy and observation for development of pheochromocytoma

Answer 55

Multiple endocrine neoplasia type 2B (MEN2B)

Question 56

What lesion? NF1 gene mutation

Answer 56

Neurofibromatosis type 1 (NF1)

Question 57

What lesion has the following clinical presentation? Multiple neurofibromas of skin and mucosa Cafe au lait macules Axillary and inguinal freckling Lisch nodules

Answer 57

Neurofibromatosis type 1 (NF1)

Question 58

What lesion? Multiple neurofibromas of skin and mucosa have potential to become malignant peripheral nerve sheath tumor

Answer 58

Neurofibromatosis type 1 (NF1)

Question 59

Light brown skin pigmentation

Answer 59

Cafe au lait macules

Question 60

Pigmentary defects of iris

Answer 60

Lisch nodules

Question 61

What lesion? Diagnosed by biopsy and genetic testing

Answer 61

Neurofibromatosis type 1 (NF1)

Question 62

What lesion? Tx = cosmetic excision of neurofibromas if possible and monitor for signs of malignant peripheral nerve sheath tumor

Answer 62

Neurofibromatosis type 1 (NF1)