Oral Path Exam 3 - Soft Tissue Masses Part 3 Flashcards
What lesion?
Caused by ectopic sebaceous glands
Fordyce granules
What lesion?
Present in over 80% of the population
Fordyce granules
What lesion?
Multiple yellow-white papules
Fordyce granules
What lesion?
Most commonly found on the buccal mucosa and vermilion of the upper lip
Fordyce granules
What lesions?
Diagnosed by biopsy
Fordyce granules
Gingival cyst of the adult
Epidermoid cyst
What lesion?
No tx necessary (variation of normal)
Fordyce granules
What lesion?
Caused by superficial dilated and tortuous veins
Varix/varicosities
What lesion?
Weakening of blood vessel walls and loss of tone in supporting CT
Varix/varicosities
What lesion?
Rare in children
Occurs in 2/3rds of people over age 60
Varix/varicosities
What lesion?
Blue-purple nodules, may be solitary or multiple
Varix/varicosities
What lesion?
Common on ventral and lateral surfaces of the tongue, lips, and buccal mucosa
Varix/varicosities
What lesion?
Can become thrombosed (firm, forms a clot)
Varix/varicosities
What lesion?
Usually a clinical diagnosis can be made, but a biopsy for solitary lesions found on the lip and buccal mucosa may be indicated
Varix/varicosities
What lesion?
No tx necessary
Varix/varicosities
What lesion?
Derived from rests of dental lamina
Gingival cyst of the adult
What lesion?
Soft tissue counterpart to lateral periodontal cyst
Gingival cyst of the adult
What lesion?
Found in adults
Gingival cyst of the adult
What lesion?
Painless, dome-like swellings that are bluish-gray in color
Gingival cyst of the adult
What lesion?
May cause “cupping out” of alveolar bone
Gingival cyst of the adult
What lesion?
Predilection for mandibular canine and premolar area
Gingival cyst of the adult
What lesion?
Always on facial gingiva/alveolar mucosa
Gingival cyst of the adult
What lesions?
Tx = excisional biopsy
Gingival cyst of the adult
Epidermoid cyst
What other lesion causes a “cupping” defect of
underlying bone?
a. Pyogenic granuloma
b. Peripheral ossifying fibroma
c. Peripheral giant cell granuloma
d. Fibroma
c. Peripheral giant cell granuloma
What lesion?
Keratin-filled cyst arising from hair follicle
Epidermoid cyst
What lesion?
Unusual before puberty
Epidermoid cyst
What lesion?
Nodular, fluctuant subcutaneous lesion
Epidermoid cyst
What lesion?
White or yellow (can be red if inflamed)
Epidermoid cyst
What lesion?
Common in acne-prone areas of head, neck, and back
Epidermoid cyst
What lesion?
NOT found intraorally
Epidermoid cyst
What lesion?
Caused by occlusion and dilation of a crypt of lymphoid tissue
Lymphoepithelial cyst
What lesion?
Most common in young adults
Lymphoepithelial cyst
What lesion?
Small submucosal mass that is white or yellow
Lymphoepithelial cyst
What lesion?
Firm or soft to palpation
Lymphoepithelial cyst
What lesion?
Commonly found on:
Floor of mouth
Ventral tongue
Posterior lateral border of tongue
Palatine tonsil
Soft palate
Lymphoepithelial cyst
What lesion?
Diagnosed clinically or by biopsy
Lymphoepithelial cyst
What lesion?
Tx = do nothing or excisional biopsy
Lymphoepithelial cyst
Which of the following is considered a variation of normal?
a. Lymphoepithelial cyst
b. Fordyce granules
c. Varix
d. Hemangioma
b. Fordyce granules
What lesion?
Caused by ectopic thyroid tissue
Lingual thyroid
What lesion?
Failure of thyroid bud to descend normally into neck
Lingual thyroid
What lesion?
More common in females
Lingual thyroid
What lesion?
Nodular mass on posterior dorsal tongue
Lingual thyroid
What lesion?
May be accompanied by dysphagia, dysphonia, and dyspnea
Lingual thyroid
What lesion?
72% are accompanied by hypothyroidism
Lingual thyroid
What lesion?
Diagnosed by thyroid scan
Lingual thyroid
What lesion?
Avoid biopsy!!
(due to risk of hemorrhage, and may be pt’s only functioning thyroid tissue)
Lingual thyroid
What lesion?
Tx = follow-up and hormone therapy if necessary (may reduce size of symptomatic lesions)
Lingual thyroid
Which of the following is found ONLY on the skin?
a. Epidermoid cyst
b. Kaposi sarcoma
c. Lymphoepithelial cyst
d. Fordyce granules
a. Epidermoid cyst
What lesion?
RET gene mutation
Multiple endocrine neoplasia type 2B (MEN2B)
What lesions?
Autosomal dominant inheritance pattern
Multiple endocrine neoplasia type 2B (MEN2B)
Neurofibromatosis type 1 (NF1)
What lesion?
Mucosal neuromas are often the first sign
Multiple endocrine neoplasia type 2B (MEN2B)
What lesion?
Mucosal neuromas tend to involve oral cavity and are soft, painless papules/nodules
Multiple endocrine neoplasia type 2B (MEN2B)
What lesion?
Mucosal neuromas primarily seen on lips and anterior tongue but can also be seen on buccal mucosa, gingiva, and palate
Multiple endocrine neoplasia type 2B (MEN2B)
What lesion has the following clinical presentation?
Mucosal neuromas
Medullary thyroid carcinoma
Pheochromocytoma (adrenal gland tumor)
Multiple endocrine neoplasia type 2B (MEN2B)
What lesion?
Diagnosed by biopsy of oral lesions and genetic testing
Multiple endocrine neoplasia type 2B (MEN2B)
What lesion?
Tx = preventative thyroidectomy and observation for development of pheochromocytoma
Multiple endocrine neoplasia type 2B (MEN2B)
What lesion?
NF1 gene mutation
Neurofibromatosis type 1 (NF1)
What lesion has the following clinical presentation?
Multiple neurofibromas of skin and mucosa
Cafe au lait macules
Axillary and inguinal freckling
Lisch nodules
Neurofibromatosis type 1 (NF1)
What lesion?
Multiple neurofibromas of skin and mucosa have potential to become malignant peripheral nerve sheath tumor
Neurofibromatosis type 1 (NF1)
Light brown skin pigmentation
Cafe au lait macules
Pigmentary defects of iris
Lisch modules
What lesion?
Diagnosed by biopsy and genetic testing
Neurofibromatosis type 1 (NF1)
What lesion?
Tx = cosmetic excision of neurofibromas if possible and monitor for signs of malignant peripheral nerve sheath tumor
Neurofibromatosis type 1 (NF1)
