Oral Path Exam 3 - Soft Tissue Masses Part 2 Flashcards

1
Q

What lesion?

Benign neoplasm derived from Schwann cells

A

Granular cell tumor

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2
Q

What lesion?

Female predilection; rare in children

A

Granular cell tumor

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3
Q

What lesion?

Sessile submucosal nodule

A

Granular cell tumor

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4
Q

What lesion?

Pink, sometimes w/ yellow hue

A

Granular cell tumor

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5
Q

What lesion?

Most common site is dorsal tongue

A

Granular cell tumor

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6
Q

What lesions?

Diagnosed by biopsy

A

Granular cell tumor
Lipoma
Hemangioma
Kaposi sarcoma
Metastatic tumor
Peripheral odontogenic cysts/tumors

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7
Q

What lesions?

Tx = excisional biopsy

A

Granular cell tumor
Lipoma
Neurofibroma
Schwannoma
Peripheral odontogenic cysts/tumors

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8
Q

What lesion?

Benign tumor of fat

A

Lipoma

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9
Q

What lesion?

Uncommon in children

A

Lipoma

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10
Q

What lesion?

Soft, smooth-surfaced nodule

A

Lipoma

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11
Q

What lesion?

Usually yellow, sometimes can be pink

A

Lipoma

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12
Q

What lesion?

Most common sites are buccal mucosa and buccal vestibule

A

Lipoma

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13
Q

What lesion?

Benign vascular tumor

A

Hemangioma

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14
Q

What lesion?

Bright red to dull blue/purple nodule

A

Hemangioma

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15
Q

What lesion?

60% in head and neck

A

Hemangioma

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16
Q

What lesion?

More common in females

A

Hemangioma

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17
Q

What lesion?

Undergo rapid growth for 6-12 months, then involute

A

Hemangioma

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18
Q

What lesion?

90% resolve by age 9

A

Hemangioma

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19
Q

What lesions?

Tx = varies depending on subtype, location, and size

A

Hemangioma
Vascular malformation

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20
Q

What lesion?

Structural anomaly of blood vessels

A

Vascular malformation

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21
Q

What lesion?

Present at birth, but persist and may become more apparent throughout life

A

Vascular malformation

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22
Q

What lesion?

Can vary from pink/red macule to blue/purple mass

A

Vascular malformation

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23
Q

What lesion?

Presentation varies based on vasculature involved (capillary, venous, arteriovenous)

A

Vascular malformation

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24
Q

What lesion?

Port wine stains are common on the face (capillary malformations)

A

Vascular malformation

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25
Q

What lesion?

Diagnosed by aspiration (to confirm origin), imaging (angiogram), and biopsy

A

Vascular malformation

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26
Q

What is the name of a helpful clinical test that involves using a glass slide to compress a lesion you think may be vascular?

A

Diascopy

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27
Q

When doing a diascopy, vascular lesions tend to ___________ with pressure. Blood is displaced and lesion returns to normal color

A

blanch

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28
Q

What lesions?

Benign; nerve origin

A

Neurofibroma
Schwannoma

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29
Q

What lesion?

Most common oral site is tongue and buccal mucosa

(but can occur in many parts of the body)

A

Neurofibroma

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30
Q

What lesion?

Most common oral site is tongue

A

Schwannoma

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31
Q

The larger the salivary gland, the more likely it is to be __________.

The smaller the salivary gland, the more likely it is to be __________.

A

benign; malignant

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32
Q

Minor salivary glands have a 50% chance of being ___________

A

malignant

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33
Q

Which salivary gland makes up 70% of neoplasms, and 24% are malignant?

A

Parotid gland

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34
Q

Most salivary gland neoplasms are found here

A

Parotid gland

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35
Q

Which salivary gland makes up 10% of neoplasms, and 24% are malignant?

A

Submandibular gland

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36
Q

Which salivary gland makes up < 1% of neoplasms, and 83% are malignant?

A

Sublingual gland

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37
Q

Not many salivary gland neoplasms are found here, but when present, likely to be malignant

A

Sublingual gland

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38
Q

Which salivary gland makes up 19% of neoplasms, and 44% are malignant?

A

Minor salivary glands

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39
Q

What lesion?

Benign or malignant

A

Salivary gland tumor

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40
Q

What lesion?

Affects major or minor salivary glands

A

Salivary gland tumor

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41
Q

What are the 3 common sites for minor salivary gland neoplasms?

A

Hard palate
Soft palate
Upper lip

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42
Q

Name the 4 salivary gland tumors

A

Pleomorphic adenoma
Mucoepidermoid carcinoma
Polymorphous adenocarcinoma
Adenoid cystic carcinoma

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43
Q

Which salivary gland tumor?

Benign

A

Pleomorphic adenoma

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44
Q

Which salivary gland tumor?

Malignant

A

Mucoepidermoid carcinoma
Polymorphous adenocarcinoma
Adenoid cystic carcinoma

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45
Q

Which salivary gland tumor?

Most common salivary gland neoplasm

A

Pleomorphic adenoma

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46
Q

Which salivary gland tumor?

Can recur

A

Pleomorphic adenoma

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47
Q

Which salivary gland tumor?

Most common salivary gland malignancy

A

Mucoepidermoid carcinoma

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48
Q

Which salivary gland tumor?

Usually low-grade

A

Mucoepidermoid carcinoma
Polymorphous adenocarcinoma

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49
Q

Which salivary gland tumor?

Not found in major salivary glands

A

Polymorphous adenocarcinoma

50
Q

Which salivary gland tumor?

More aggressive (perineural invasion)

A

Adenoid cystic carcinoma

51
Q

What lesion?

Tx varies depending on benign vs malignant, location, histopathologic grade, and clinical stage

A

Salivary gland tumor

52
Q

What lesion?

Tx = surgical excision, wide surgical excision, superficial parotidectomy, or total gland removal with or without neck dissection

A

Salivary gland tmor

53
Q

One patient has a salivary gland neoplasm in their parotid gland and one patient has a salivary gland neoplasm in their sublingual gland.

Which is more likely to be malignant?

A

Sublingual gland neoplasm

54
Q

What is the most common salivary gland
malignancy?

a. Pleomorphic adenoma
b. Mucoepidermoid carcinoma
c. Polymorphous adenocarcinoma
d. Adenoid cystic carcinoma

A

b. Mucoepidermoid carcinoma

55
Q

What is the most common salivary gland neoplasm?

a. Pleomorphic adenoma
b. Mucoepidermoid carcinoma
c. Polymorphous adenocarcinoma
d. Adenoid cystic carcinoma

A

a. Pleomorphic adenoma

56
Q

What is the most common site for a minor salivary gland neoplasm?

a. Gingiva
b. Hard palate
c. Ventral tongue
d. Floor of mouth

A

b. Hard palate

57
Q

What lesion?

Group of malignancies characterized by overproduction of neoplastic WBCs

58
Q

What lesion?

Originates in bone marrow, then spills over into circulating blood and tissues

59
Q

What lesion?

Affects broad range of people

A

Leukemia
Lymphoma
Peripheral odontogenic cysts/tumors

60
Q

What lesion?

Symptoms include fatigue, dyspnea, splenomegaly, hepatomegaly, lymphadenopathy, easy bruising/bleeding, fever

61
Q

What lesion?

Diffuse, boggy, non-tender swelling of gingiva, with or without ulceration, asymptomatic

62
Q

Acute or chronic leukemia?

More common in children and young adults

63
Q

Acute or chronic leukemia?

Proliferation of immature WBCs

64
Q

Acute or chronic leukemia?

More aggressive clinical course

65
Q

Acute or chronic leukemia?

Occurs most frequently in middle-aged adults

66
Q

Acute or chronic leukemia?

Proliferation of mature WBCs

67
Q

Acute or chronic leukemia?

Slowly progressive clinical course

68
Q

What is the histogenesis for leukemia?

A

Lymphocytic/lymphoblastic
Myeloid

69
Q

What does CLL stand for?

A

Chronic lymphocytic leukemia

70
Q

What lesion?

Diagnosed by biopsy and bone marrow biopsy

71
Q

What lesion?

Tx = chemo and bone marrow transplant

72
Q

What lesion?

Group of malignant tumors of lymph nodes

73
Q

What lesion?

Originates in lymph nodes then can become more widely disseminated

74
Q

What lesion?

Enlarging, non-tender, discrete mass in lymph node region

75
Q

What lesion?

May have weight loss, fever, night sweats, and pruritus

76
Q

What lesion?

Oral non-tender, diffuse soft tissue swelling

(most commonly diffuse large B cell lymphoma)

77
Q

What lesion?

Most common oral sites are buccal vestibule, posterior hard palate, and gingiva

78
Q

What lesion?

Diagnosed by biopsy and imaging

79
Q

What lesion?

Tx = chemo

80
Q

What lesion?

Vascular malignancy

A

Kaposi sarcoma

81
Q

What lesion?

Caused by infection with human herpesvirus 8 (HHV-8)

A

Kaposi sarcoma

82
Q

What lesion?

Most commonly seen in pts with AIDS in the US

A

Kaposi sarcoma

83
Q

What lesion?

Classic form seen in the Med, eastern Europe, and central equatorial Africa

A

Kaposi sarcoma

84
Q

What lesion?

Endemic form seen in Africa

A

Kaposi sarcoma

85
Q

What lesion?

Iatrogenic form seen in recipients of solid organ transplants

A

Kaposi sarcoma

86
Q

What lesion?

90% in men

A

Kaposi sarcoma

87
Q

What lesion?

Multiple blue/purple macules, plaques, and nodules on the face and oral mucosa

A

Kaposi sarcoma

88
Q

What lesion?

Predilection for hard palate, gingiva, and tongue

A

Kaposi sarcoma

89
Q

What lesion?

Tx = varies, usually involves management of AIDS and chemo

A

Kaposi sarcoma

90
Q

What type of Kaposi sarcoma is most common in the United States?

a. Classic
b. Endemic
c. Iatrogenic
d. AIDS-related

A

d. AIDS-related

91
Q

What lesion?

Spread of malignancy from another site

A

Metastatic tumors

92
Q

What lesion?

Affects middle aged and older adults with cancer

A

Metastatic tumors

93
Q

What are the common sites of origin for metastatic tumors for men?

A

Lung
Kidney
Melanoma

94
Q

What are the common sites of origin for metastatic tumors for women?

A

Lung
Kidney
Breast
Genital

95
Q

What lesion?

Nodular soft tissue mass resembling hyperplastic or reactive growth

A

Metastatic tumor

96
Q

What lesion?

Most common oral site is the gingiva

A

Metastatic tumor

97
Q

What lesion?

In 25% of pts, the primary malignancy is not diagnosed at time of oral metastasis presentation

A

Metastatic tumor

98
Q

What lesion?

Tx = management of primary malignancy

A

Metastatic tumor

99
Q

What lesion?

Poor prognosis

A

Metastatic tumor

100
Q

What lesion has the following etiologies?

Goiter (most common)
Thyroid adenoma (benign)
Thyroid carcinoma (malignant)
Graves disease (more likely to be symptomatic)
Hashimoto’s thyroiditis (more likely to be symptomatic)

A

Thyroid gland enlargement

101
Q

What lesion?

Mass in anterior midline of neck

A

Thyroid gland enlargement

102
Q

What lesion?

Diffuse thyroid enlargement

A

Graves disease (hyperthyroidism)

103
Q

What lesion?

Weight loss despite increased appetite

A

Graves disease (hyperthyroidism)

104
Q

What lesion?

Tachycardia

A

Graves disease (hyperthyroidism)

105
Q

What lesion?

Excessive perspiration

A

Graves disease (hyperthyroidism)

106
Q

What lesion?

Warm, smooth skin

A

Graves disease (hyperthyroidism)

107
Q

What lesion?

Tremors

A

Graves disease (hyperthyroidism)

108
Q

What lesion?

Exophthalmos

A

Graves disease (hyperthyroidism)

109
Q

What lesion?

Lethargy

A

Hashimoto’s thyroiditis (hypothyroidism)

110
Q

What lesion?

Dry, course skin

A

Hashimoto’s thyroiditis (hypothyroidism)

111
Q

What lesion?

Swelling of face and extremities

A

Hashimoto’s thyroiditis (hypothyroidism)

112
Q

What lesion?

Huskiness of voice

A

Hashimoto’s thyroiditis (hypothyroidism)

113
Q

What lesion?

Constipation

A

Hashimoto’s thyroiditis (hypothyroidism)

114
Q

What lesion?

Bradycardia

A

Hashimoto’s thyroiditis (hypothyroidism)

115
Q

What lesion?

Hypothermia

A

Hashimoto’s thyroiditis (hypothyroidism)

116
Q

What lesion?

Diagnosed by fine needle aspiration, imaging, and bloodwork

A

Thyroid gland enlargement

117
Q

What lesion?

Tx = varies based on etiology

A

Thyroid gland enlargement

118
Q

What lesion?

Odontogenic neoplasms like peripheral ameloblastoma, peripheral calcifying epithelial odontogenic tumor, etc

A

Peripheral odontogenic cysts/tumors

119
Q

What lesion?

Soft tissue mass on the gingiva

A

Peripheral odontogenic cysts/tumors

120
Q

What is the most common oral soft tissue site for metastatic cancer?