Oral Path Exam 3 - Soft Tissue Masses Part 2 Flashcards
1
Q
What lesion?
Benign neoplasm derived from Schwann cells
A
Granular cell tumor
2
Q
What lesion?
Female predilection; rare in children
A
Granular cell tumor
3
Q
What lesion?
Sessile submucosal nodule
A
Granular cell tumor
4
Q
What lesion?
Pink, sometimes w/ yellow hue
A
Granular cell tumor
5
Q
What lesion?
Most common site is dorsal tongue
A
Granular cell tumor
6
Q
What lesions? (6)
Diagnosed by biopsy
A
Granular cell tumor
Lipoma
Hemangioma
Kaposi sarcoma
Metastatic tumor
Peripheral odontogenic cysts/tumors
7
Q
What lesions? (5)
Tx = excisional biopsy
A
Granular cell tumor
Lipoma
Neurofibroma
Schwannoma
Peripheral odontogenic cysts/tumors
8
Q
What lesion?
Benign tumor of fat
A
Lipoma
9
Q
What lesion?
Uncommon in children
A
Lipoma
10
Q
What lesion?
Soft, smooth-surfaced nodule
A
Lipoma
11
Q
What lesion?
Usually yellow, sometimes can be pink
A
Lipoma
12
Q
What lesion?
Most common sites are buccal mucosa and buccal vestibule
A
Lipoma
13
Q
What lesion?
Benign vascular tumor
A
Hemangioma
14
Q
What lesion?
Bright red to dull blue/purple nodule
A
Hemangioma
15
Q
What lesion?
60% in head and neck
A
Hemangioma
16
Q
What lesion?
More common in females
A
Hemangioma
17
Q
What lesion?
Undergo rapid growth for 6-12 months, then involute
A
Hemangioma
18
Q
What lesion?
90% resolve by age 9
A
Hemangioma
19
Q
What lesions?
Tx = varies depending on subtype, location, and size
A
Hemangioma
Vascular malformation
20
Q
What lesion?
Structural anomaly of blood vessels
A
Vascular malformation
21
Q
What lesion?
Present at birth, but persist and may become more apparent throughout life
A
Vascular malformation
22
Q
What lesion?
Can vary from pink/red macule to blue/purple mass
A
Vascular malformation
23
Q
What lesion?
Presentation varies based on vasculature involved (capillary, venous, arteriovenous)
A
Vascular malformation
24
Q
What lesion?
Port wine stains are common on the face (capillary malformations)
A
Vascular malformation
25
What lesion?
Diagnosed by aspiration (to confirm origin), imaging (angiogram), and biopsy
Vascular malformation
26
What is the name of a helpful clinical test that involves using a glass slide to compress a lesion you think may be vascular?
Diascopy
27
When doing a diascopy, vascular lesions tend to ___________ with pressure. Blood is displaced and lesion returns to normal color
blanch
28
What lesions?
Benign; nerve origin
Neurofibroma
Schwannoma
29
What lesion?
Most common oral site is tongue and buccal mucosa
(but can occur in many parts of the body)
Neurofibroma
30
What lesion?
Most common oral site is tongue
Schwannoma
31
The larger the salivary gland, the more likely it is to be __________.
The smaller the salivary gland, the more likely it is to be __________.
benign; malignant
32
Minor salivary glands have a 50% chance of being ___________
malignant
33
Which salivary gland makes up 70% of neoplasms, and 24% are malignant?
Parotid gland
34
Most salivary gland neoplasms are found here
Parotid gland
35
Which salivary gland makes up 10% of neoplasms, and 24% are malignant?
Submandibular gland
36
Which salivary gland makes up < 1% of neoplasms, and 83% are malignant?
Sublingual gland
37
Not many salivary gland neoplasms are found here, but when present, likely to be malignant
Sublingual gland
38
Which salivary gland makes up 19% of neoplasms, and 44% are malignant?
Minor salivary glands
39
What lesion?
Benign or malignant
Salivary gland tumor
40
What lesion?
Affects major or minor salivary glands
Salivary gland tumor
41
What are the 3 common sites for minor salivary gland neoplasms?
Hard palate
Soft palate
Upper lip
42
Name the 4 salivary gland tumors
Pleomorphic adenoma
Mucoepidermoid carcinoma
Polymorphous adenocarcinoma
Adenoid cystic carcinoma
43
Which salivary gland tumor?
Benign
Pleomorphic adenoma
44
Which salivary gland tumor?
Malignant
Mucoepidermoid carcinoma
Polymorphous adenocarcinoma
Adenoid cystic carcinoma
45
Which salivary gland tumor?
Most common salivary gland neoplasm
Pleomorphic adenoma
46
Which salivary gland tumor?
Can recur
Pleomorphic adenoma
47
Which salivary gland tumor?
Most common salivary gland malignancy
Mucoepidermoid carcinoma
48
Which salivary gland tumor?
Usually low-grade
Mucoepidermoid carcinoma
Polymorphous adenocarcinoma
49
Which salivary gland tumor?
Not found in major salivary glands
Polymorphous adenocarcinoma
50
Which salivary gland tumor?
More aggressive (perineural invasion)
Adenoid cystic carcinoma
51
What lesion?
Tx varies depending on benign vs malignant, location, histopathologic grade, and clinical stage
Salivary gland tumor
52
What lesion?
Tx = surgical excision, wide surgical excision, superficial parotidectomy, or total gland removal with or without neck dissection
Salivary gland tmor
53
One patient has a salivary gland neoplasm in their parotid gland and one patient has a salivary gland neoplasm in their sublingual gland.
Which is more likely to be malignant?
Sublingual gland neoplasm
54
What is the most common salivary gland
malignancy?
a. Pleomorphic adenoma
b. Mucoepidermoid carcinoma
c. Polymorphous adenocarcinoma
d. Adenoid cystic carcinoma
b. Mucoepidermoid carcinoma
55
What is the most common salivary gland neoplasm?
a. Pleomorphic adenoma
b. Mucoepidermoid carcinoma
c. Polymorphous adenocarcinoma
d. Adenoid cystic carcinoma
a. Pleomorphic adenoma
56
What is the most common site for a minor salivary gland neoplasm?
a. Gingiva
b. Hard palate
c. Ventral tongue
d. Floor of mouth
b. Hard palate
57
What lesion?
Group of malignancies characterized by overproduction of neoplastic WBCs
Leukemia
58
What lesion?
Originates in bone marrow, then spills over into circulating blood and tissues
Leukemia
59
What lesion? (3)
Affects broad range of people
Leukemia
Lymphoma
Peripheral odontogenic cysts/tumors
60
What lesion?
Symptoms include fatigue, dyspnea, splenomegaly, hepatomegaly, lymphadenopathy, easy bruising/bleeding, fever
Leukemia
61
What lesion?
Diffuse, boggy, non-tender swelling of gingiva, with or without ulceration, asymptomatic
Leukemia
62
Acute or chronic leukemia?
More common in children and young adults
Acute
63
Acute or chronic leukemia?
Proliferation of immature WBCs
Acute
64
Acute or chronic leukemia?
More aggressive clinical course
Acute
65
Acute or chronic leukemia?
Occurs most frequently in middle-aged adults
Chronic
66
Acute or chronic leukemia?
Proliferation of mature WBCs
Chronic
67
Acute or chronic leukemia?
Slowly progressive clinical course
Chronic
68
What is the histogenesis for leukemia?
Lymphocytic/lymphoblastic
Myeloid
69
What does CLL stand for?
Chronic lymphocytic leukemia
70
What lesion?
Diagnosed by biopsy and bone marrow biopsy
Leukemia
71
What lesion?
Tx = chemo and bone marrow transplant
Leukemia
72
What lesion?
Group of malignant tumors of lymph nodes
Lymphoma
73
What lesion?
Originates in lymph nodes then can become more widely disseminated
Lymphoma
74
What lesion?
Enlarging, non-tender, discrete mass in lymph node region
Lymphoma
75
What lesion?
May have weight loss, fever, night sweats, and pruritus
Lymphoma
76
What lesion?
Oral non-tender, diffuse soft tissue swelling
(most commonly diffuse large B cell lymphoma)
Lymphoma
77
What lesion?
Most common oral sites are buccal vestibule, posterior hard palate, and gingiva
Lymphoma
78
What lesion?
Diagnosed by biopsy and imaging
Lymphoma
79
What lesion?
Tx = chemo
Lymphoma
80
What lesion?
Vascular malignancy
Kaposi sarcoma
81
What lesion?
Caused by infection with human herpesvirus 8 (HHV-8)
Kaposi sarcoma
82
What lesion?
Most commonly seen in pts with AIDS in the US
Kaposi sarcoma
83
What lesion?
Classic form seen in the Med, eastern Europe, and central equatorial Africa
Kaposi sarcoma
84
What lesion?
Endemic form seen in Africa
Kaposi sarcoma
85
What lesion?
Iatrogenic form seen in recipients of solid organ transplants
Kaposi sarcoma
86
What lesion?
90% in men
Kaposi sarcoma
87
What lesion?
Multiple blue/purple macules, plaques, and nodules on the face and oral mucosa
Kaposi sarcoma
88
What lesion?
Predilection for hard palate, gingiva, and tongue
Kaposi sarcoma
89
What lesion?
Tx = varies, usually involves management of AIDS and chemo
Kaposi sarcoma
90
What type of Kaposi sarcoma is most common in the United States?
a. Classic
b. Endemic
c. Iatrogenic
d. AIDS-related
d. AIDS-related
91
What lesion?
Spread of malignancy from another site
Metastatic tumors
92
What lesion?
Affects middle aged and older adults with cancer
Metastatic tumors
93
What are the common sites of origin for metastatic tumors for men?
Lung
Kidney
Melanoma
94
What are the common sites of origin for metastatic tumors for women?
Lung
Kidney
Breast
Genital
95
What lesion?
Nodular soft tissue mass resembling hyperplastic or reactive growth
Metastatic tumor
96
What lesion?
Most common oral site is the gingiva
Metastatic tumor
97
What lesion?
In 25% of pts, the primary malignancy is not diagnosed at time of oral metastasis presentation
Metastatic tumor
98
What lesion?
Tx = management of primary malignancy
Metastatic tumor
99
What lesion?
Poor prognosis
Metastatic tumor
100
What lesion has the following etiologies?
Goiter (most common)
Thyroid adenoma (benign)
Thyroid carcinoma (malignant)
Graves disease (more likely to be symptomatic)
Hashimoto’s thyroiditis (more likely to be symptomatic)
Thyroid gland enlargement
101
What lesion?
Mass in anterior midline of neck
Thyroid gland enlargement
102
What lesion?
Diffuse thyroid enlargement
Graves disease (hyperthyroidism)
103
What lesion?
Weight loss despite increased appetite
Graves disease (hyperthyroidism)
104
What lesion?
Tachycardia
Graves disease (hyperthyroidism)
105
What lesion?
Excessive perspiration
Graves disease (hyperthyroidism)
106
What lesion?
Warm, smooth skin
Graves disease (hyperthyroidism)
107
What lesion?
Tremors
Graves disease (hyperthyroidism)
108
What lesion?
Exophthalmos
Graves disease (hyperthyroidism)
109
What lesion?
Lethargy
Hashimoto's thyroiditis (hypothyroidism)
110
What lesion?
Dry, course skin
Hashimoto's thyroiditis (hypothyroidism)
111
What lesion?
Swelling of face and extremities
Hashimoto's thyroiditis (hypothyroidism)
112
What lesion?
Huskiness of voice
Hashimoto's thyroiditis (hypothyroidism)
113
What lesion?
Constipation
Hashimoto's thyroiditis (hypothyroidism)
114
What lesion?
Bradycardia
Hashimoto's thyroiditis (hypothyroidism)
115
What lesion?
Hypothermia
Hashimoto's thyroiditis (hypothyroidism)
116
What lesion?
Diagnosed by fine needle aspiration, imaging, and bloodwork
Thyroid gland enlargement
117
What lesion?
Tx = varies based on etiology
Thyroid gland enlargement
118
What lesion?
Odontogenic neoplasms like peripheral ameloblastoma, peripheral calcifying epithelial odontogenic tumor, etc
Peripheral odontogenic cysts/tumors
119
What lesion?
Soft tissue mass on the gingiva
Peripheral odontogenic cysts/tumors
120
What is the most common oral soft tissue site for metastatic cancer?
Gingiva
