Implants - Lecture 5: Wound Healing & Anatomical Considerations Flashcards
Layer of fibrous CT formed between a dental implant and surrounding bone
Fibro-osseous integration
Initially good success rates, but extremely poor long-term success; seen in earlier implant systems
Fibro-osseous integration
Considered a “failed implant” by today’s standards; no bone direct contact w/ implant
Fibro-osseous integration
Tissue-to-implant contact
Fibro-osseous integration
The direct contact between living bone and a
functionally loaded dental implant surface
without interposed soft tissue at the light
microscope level
Osseointegration
Bone-to-implant contact
Osseointegration
A time-dependent healing process whereby
clinically asymptomatic rigid fixation of
implant is achieved and maintained in bone
during functional loading
Osseointegration
Clot forms within minutes
Hemostasis
Recruitment of immune cells
Inflammation
Angiogenesis of fibroblast activity
Proliferation
Maturation of bone (osseointegration)
Remodeling
What are the 4 phases of healing for an implant?
Hemostasis
Inflammation
Proliferation
Remodeling
Time after implant placement?
Blood clot is in contact with the implant surface: erythrocytes, neutrophils, and macrophages are trapped in a network of fibrin
First few hours
Time after implant placement?
The clot is replaced by granulation tissue
composed by mesenchymal cells; disorganized CT matrix and the first vessel
sprouts are evident
3-4 days
Time after implant placement?
Most of the inflammatory cells are resorbed and immature woven bone can be evidenced
together with newly formed vessels
1 week
Time after implant placement?
Woven bone formation is more pronounced and surrounds the whole implant mixed with old bone which is a clear sign of osteogenesis. Osteoclast formation is
evidenced and contributes to bone remodeling
2 weeks
Time after implant placement?
Newly formed mineralized bone extends from the prepared bone surface to the implant coating
4 weeks
Time after implant placement?
Bone enters the remodeling phase, more
mature bone with the presence of primary and secondary osteons is evident
6-12 weeks
What are the 2 types of stability involved with osseointegration?
Initial
Secondary
The degree of tightness of a dental implant immediately after placement in its prepared osteotomy
Initial stability
An implant is considered to have initial stability if it is clinically _________ at the time of placement
immobile
The fixation of a dental implant to the bone over time and after osseointegration has occurred
Secondary stability
Bone interface is stronger on the day of implant placement compared to ___________ later
3 months
What is needed for osseointegration?
- Biocompatible material (the implant)
- Atraumatic surgery to minimize tissue damage
- Implant placement in intimate contact w/ bone
- Immobility of the implant during healing
Supporting bone in _________ contact w/ implant surface (no PDL)
direct
Fibers running parallel to implant surface and no inserting fibers
CT zone
What 3 factors influence healing?
Systemic
Local
Technique
What are 3 systemic factors that influence healing?
Smoking
Diabetes
Meds (bisphosphonates)
What are 3 local factors that influence healing?
Surgical trauma
Implant surface
Infection
What are 3 technique factors that influence healing?
Flapless
Open surgery
Smokers have ________ as many implant failures than non-smokers
twice
Smokers have decreased resistance to ____________ and ____________
inflammation; infection
Smokers have high failure rates of ___________ and ___________
implants; bone grafts
In regards to smoking, what is a relative contraindication for implants?
Any amount of smoking
In regards to smoking, what is an absolute contraindication for implants?
Excessive smoking (more than 1.5 packs/day)
There is a direct correlation btwn osseointegration and ___________ control
glycemic
Diabetics patients are prone to developing _____________ and ___________ complications
infection; vascular
In regards to diabetes, what is a relative contraindication for implants?
Insulin-controlled diabetes
In regards to diabetes, what is not a contraindication for implants?
Well-controlled diabetes
What are bisphosphonates used to treat?
Osteoporosis
Metastatic bone cancer
Paget disease
Reduce bone resorption via direct effect on osteoclasts
Bisphosphonates
Can cause drug-induced necrosis of the jaw
Bisphosphonates
In regards to bisphosphonates, what is a relative contraindication for implants?
Oral bisphosphonates
In regards to bisphosphonates, what is an absolute contraindication for implants?
IV bisphosphonates
The surgical process of the implant osteotomy preparation and implant insertion results in a regional acceleratory phenomenon of bone repair around the implant interface
Surgical trauma
The implant-bone interface is weakest and most at risk for overload at _________ weeks after surgical insertion because the surgical trauma causes bone remodeling at the interface
3-6 weeks
Proven to be critical for adhesion and differentiation of cells during the bone remodeling process essential to osseointegration
Implant surface
In regards to implant surface, what usually has weaker bone integration?
Smooth
Minimally rough
In regards to implant surface, what usually has stronger bone integration?
Moderately rough
What type of implant surface?
0-0.4 um
Smooth
What type of implant surface?
0.5-1 um
Minimally rough
What type of implant surface?
1-2 um
Moderately rough
What 4 parts of the implant surface are directly related to an increased success rate?
Increased SA
Increased cellular attachment
Increased primary stability
Increased bone implant contact
What is the effect on the implant surface?
Etching w/ acid
Blasting w/ an abrasive material
Tx w/ lasers
Subtractive
What is the effect on the implant surface?
Hydroxyapatite coating and titanium plasma spraying
Oxidation or anodization
Additive
Pros: less invasive, maintains tissue vasculature, no vertical incisions, less discomfort
Cons: malpositioning (unless guided)
Open surgery x flapless
Bone quality in the posterior maxilla is typically the __________ of any area
poorest
Bone resorption and increased _____________ of the sinus
pneumatization
Vital structures that define anatomic limitations of implant placement
Nasal cavity
Incisive canal
Implants should be placed _____ mm short of the nasal floor and should not be placed in the maxillary __________
1 mm; midline
The anterior loop of IAN measurement should be added to the _____ mm safety zone to ensure adequate space between the implant and the foramen
2 mm
There is a minimum ______ mm safe distance btwn an implant and IAN
2 mm
What is super important to make sure the IAN is ok?
Pre, intra, and post-op PAs
(and take CBCT if not sure)
Used for general assessment
Pano
Used for precise anatomic mapping
CBCT