Oral Path Exam 2 - Papillary Growths Flashcards
What lesion?
Double-stranded DNA virus
HPV
What lesion?
Infects epithelial cells (cutaneous and mucous membranes)
HPV
What lesion?
> 200 types in humans
HPV
What lesion?
Associated with benign, potentially malignant, and malignant epithelial lesions
HPV
How many types of HPV infect the oral mucosa?
> 30 types
What HPV type is associated with oral squamous papilloma?
6, 11
What HPV type is associated with oropharyngeal squamous cell carcinoma?
16
What HPV type is associated with verruca vulgaris?
2
What HPV type is associated with condyloma acuminatum?
6, 11
When did the HPV vaccine become routine?
2006
What is the current HPV vaccine?
9-valent (Gardasil 9)
The HPV vaccine is recommended for all adolescents ages _________
11-12
What is the HPV vaccine indicated for prevention of?
Genital warts
Precancers/cancers of cervix, vulva, vagina, anus
Oropharyngeal and other HN cancers
What lesion?
Caused by benign proliferation of stratified squamous epithelium
Squamous papilloma
What lesion?
Diagnosed most often btwn 30-50 yrs old
Squamous papilloma
What lesion?
White or pink exophytic nodule w/ fingerlike surface projections
Squamous papilloma
What lesion?
Often pedunculated
Squamous papilloma
What lesion?
Commonly found on soft palate, tongue, and lips
Squamous papilloma
What lesion?
Can be difficult to differentiate from verruca vulgaris, condyloma acuminatum, and others clinically
Squamous papilloma
What lesions?
Diagnosed by biopsy
Squamous papilloma
Condyloma acuminatum
What lesion?
Tx = excisional biopsy
Squamous papilloma
What lesion?
Caused by benign hyperplasia of stratified squamous epithelium
Verruca vulgaris (“common wart”)
What lesions?
Contagious
Verruca vulgaris (“common wart”)
Condyloma acuminatum
What lesion?
Most common in kids
Verruca vulgaris (“common wart”)
What lesion?
Painless papule w/ papillary projections or rough, pebbly surface
Verruca vulgaris (“common wart”)
What lesion?
Can have multiple or clustered lesions
Verruca vulgaris (“common wart”)
What lesion?
Skin of hands is most common
Verruca vulgaris (“common wart”)
What lesion?
Most common oral sites are vermilion border, labial mucosa, and anterior tongue
Verruca vulgaris (“common wart”)
What lesion?
Diagnosed clinically and biopsy
Verruca vulgaris (“common wart”)
What lesion?
Can resolve spontaneously (2/3rds resolve within 2 yrs)
Verruca vulgaris (“common wart”)
What lesion?
Tx = topical salicylic acid, cryotherapy, surgical excision
Verruca vulgaris (“common wart”)
What is the first line tx for verruca vulgaris found in the mouth?
Surgical excision
What lesion?
Caused by proliferation of stratified squamous epithelium
Condyloma acuminatum
What lesion?
Common sexually transmitted disease
Condyloma acuminatum
What lesion?
Often found in teenagers and young adults
Condyloma acuminatum
What lesion?
Most commonly anogenital
Condyloma acuminatum
What lesion?
Oral lesions most frequently on labial mucosa and lingual frenum
Condyloma acuminatum
What lesion?
Sessile
Pink
Exophytic mass
Short, blunted surface projections
Condyloma acuminatum
What lesion?
Larger than squamous papillomas
Condyloma acuminatum
What lesion?
May be single or clustered
Condyloma acuminatum
What lesion?
Tx = excisional biopsy, cryotherapy, or laser ablation
Condyloma acuminatum
What lesion?
Caused by ill-fitting denture, poor denture hygiene, wearing denture 24 hrs/day
Inflammatory papillary hyperplasia
What lesion?
Effects denture or retainer wearers
Inflammatory papillary hyperplasia
What lesion?
Can also occur in pts w/ high palatal vault and mouth breathers
Inflammatory papillary hyperplasia
What lesion?
Usually asymptomatic
Inflammatory papillary hyperplasia
What lesion?
Erythematous pebbly or papillary mucosa
Inflammatory papillary hyperplasia
What lesion?
Midportion of hard palate most frequently affected
Inflammatory papillary hyperplasia
What lesion?
Diagnosed clinically, but biopsy can be done if there is any doubt
Inflammatory papillary hyperplasia
What lesion?
Tx = improve denture hygiene/remake ill-fitting denture; antifungal if indicated
Inflammatory papillary hyperplasia
What are 3 other important diagnoses that may appear papillary?
Proliferative verrucous leukoplakia (PVL)
Squamous cell carcinoma
Verrucous carcinoma
T/F: PVL, SCC, and verrucous carcinoma are generally going to show more persistent, continuous growth and will grow bigger than most HPV lesions
True
What is the gold standard for accurate diagnosis?
Biopsy
