Oher beta lactams/ polypeptides Flashcards
Antibiotics with the broadest activity, resistant to betalactamases
Carbapenems
Carbapenem that undergoes cleavage by dihydropeptidase
Imipenem
Inibits cleavage by dihydropeptidase
Cilastatin
[cleavage ni kulas]
Beta-lactam ring is not fused to another ring
Monobactam
imipenem and carbapenem adverse reaction
seizures
[im in car (imicar)]
Polypeptide clinical use is limited because of?
renal toxicity
[polypeptide all cin]
only systemic polypeptide
vancomycin
Effective against MRSA, pseudomembranous colitis by c. difficile
vancomycin
vancomycin adverse reaction
redman syndrome
[redvan]
topical, cyclic peptide or a mixture of polypeptide, poorly absorbed, active against a wide variety of gram(+) organisms
Bacitracin
[base:skin]