Oher beta lactams/ polypeptides Flashcards

1
Q

Antibiotics with the broadest activity, resistant to betalactamases

A

Carbapenems

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2
Q

Carbapenem that undergoes cleavage by dihydropeptidase

A

Imipenem

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3
Q

Inibits cleavage by dihydropeptidase

A

Cilastatin

[cleavage ni kulas]

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4
Q

Beta-lactam ring is not fused to another ring

A

Monobactam

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5
Q

imipenem and carbapenem adverse reaction

A

seizures

[im in car (imicar)]

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6
Q

Polypeptide clinical use is limited because of?

A

renal toxicity

[polypeptide all cin]

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7
Q

only systemic polypeptide

A

vancomycin

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8
Q

Effective against MRSA, pseudomembranous colitis by c. difficile

A

vancomycin

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9
Q

vancomycin adverse reaction

A

redman syndrome

[redvan]

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10
Q

topical, cyclic peptide or a mixture of polypeptide, poorly absorbed, active against a wide variety of gram(+) organisms

A

Bacitracin

[base:skin]

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