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ASS PHARMA > antifungals > Flashcards

antifungals Flashcards

1
Q

Interferes with cell wall synthesis/permeability via inibition of B-(1,3)-D-glucan synthesis.
Effective against most candida but no cryptococcus

A

Echinocandins

[candins: candidiasis]

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2
Q

Echinocandin Effective against invasive aspergillosis, candida

A

Caspofungin

[caspa: aspergillosis]

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3
Q

MOA: interacts with c-14 a demethylase to block demethylation of Lanosterol to ergosterol

A

Azoles

[14 azz holes on meth]

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4
Q

azole, Inhibits androgen and adrenal steroid synthesis, SE gynecomastia

A

Ketoconazole

[keta totoy]

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5
Q

azole without the endocrinologic effects of ketoconazole

A

Itraconazole

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6
Q

DOC for cryptococcal meningitis

A

Fluconazole

[fLuck crypt]

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7
Q

Subcutaneous and systemic mycoses DOC (3)

A

Fluconazole, Ketoconazole, Itraconazole

amp! [fLuck Cute Tira]

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8
Q

superficial mycoses DOC (3)

A

Clotrimazle, Miconazole, Econazole

[CoME]

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9
Q

Polyene antifungal that binds to Ergosterol present in the cell membrane. DOC for systemic mycoses

A

Amphotericin B

amp! [fLuck Cute Tira]

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10
Q

Polyene antifungal for oral candidiasis

A

Nystatin

[oral: nice!]

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11
Q

Allylamines (2)

A

Naftifine
Terbinafine
(fine! Ali Na Ter!)

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12
Q

Benzylamines

A

Butenafine

riding a Benz? Buti na fine!

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13
Q

interacts with microtubules of fungus, arrests cell division in metaphase

A

Griseofulvin

Ulvin was arrested

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14
Q

Nucleoside with synergistic effect to amphotericin B in the treatment of systemic mycoses and meningitis by c. neoformans

A

flucytosine

[amp!Lucy]

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ASS PHARMA (16 decks)

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