Antimalarials Flashcards

1
Q

strutural feature of all antimalarials

A

Quinoline ring

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2
Q

reserved for malarial strains resistant to other agents

A

Quinine

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3
Q

major adverse effect of quinine

A

cinchonism (nausea, vomiting, tinnitus, vertigo)

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4
Q

DOC for Falcifarum malaria, extraintestinal amoebias

A

Chloroquine

[chloro:falci, klaro:false]

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5
Q

antimalarial with anti inflammatory action, used in RA, lupus

A

Hydroxychloroquine

[hydro: rehydrate pts with RA, Lupus]

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6
Q

Highly suppressive in Plasmodium vivax and P. falciparum

A

Amodiaquine

[suppressive ang amo]

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7
Q

Effective only against the exoerythrocytic stages of malaria, gametocidal in all 4 plasmodia species

A

Primaquine

[Prime exo]

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8
Q

antimalarial primarily used in the treatment of Giardiasis, also effective against tapeworm and malaria, topically against leishmaniasis

A

Quinacrine

[Queen’s guard]

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9
Q

Effective as single agent for suppressing and curing multidrug resistant form of plasmodium falciparum

A

Mefloquine

[single:me, false]

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