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ASS PHARMA > CNS drugs > Flashcards

CNS drugs Flashcards

1
Q

drugs most important for anxiety states and insomnia

A

Benzodiazepines (ex Flumenazil)

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2
Q

drugs that facilitate GABAa action

A

Barbiturates (Thiopental, Phenobarbital)

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3
Q

rare metabolic disorder that is characterized by deficiency of the enzyme as hydroxymethylbilane synthase (also known as porphobilinogen deaminase)

A

acute intermittent porphyria

(baribiturates is contraindicated)

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4
Q

drugs that block Na channels, inhibit glutamate release

A

Phenytoin

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5
Q

AE: gingival hyperplasia, teratigenic, fetal hydantoin syndrome

A

Phenytoin

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6
Q

DOC for partial and GTC seizures, trigeminal neuralgia

A

Phenytoin

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7
Q

DOC for febrile seizures

A

Phenobarbital

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8
Q

MOA Blocks voltage gated Na channels, inc GABA concentration

A

Valproic acid

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9
Q

MOA inhibits Calcium influx, used for absence seizuresq

A

Ethosuximide

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10
Q

Fatal blood level of ethanol

A

400mg/DL

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11
Q

ethanol causes this condition

A

Wernicke-korsakoff syndrome

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12
Q

drugs with disulfiram-like reactions (3)

A

metronidazole, cephalosporins, procarbazine

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13
Q

MOA: blocks reuptake of norepi and serotonin

blocks effects of clonidine

A

Tricyclic antidepressants

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14
Q

Tricyclic antidepressant for bedwetters

A

imipramine

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15
Q

least sedating Tricyclic antidepressant

A

desipramine

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16
Q

MOA: Serotonin specific inhibitors

A

SSRIs

ex. Fluoxetin

17
Q

SE of Monoamine oxidase inhibitors( MAOIS) + tyramin rich food causes

A

hypertensive crisis

18
Q

SE of Monoamine oxidase inhibitors( MAOIS) + TCA

A

convulsions, coma

19
Q

SE of Monoamine oxidase inhibitors( MAOIS) + SSRI

A 
Serotonin syndrome
(hyperthermia, muscle rigidity, myoclonus, MS changes)
20
Q

DOC for tourette’s syndrome

A

haloperidol

21
Q

DOC for intractable hiccups

A

chlorpromazine

22
Q

DOC for antipruritic therapy

A

promethazine

23
Q

specie strychous which chiefly contains quarternary neuromuscular blocking alkaloids

A

curare

ASS PHARMA (16 decks)

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