nucleic acids and other nucleotides Flashcards

1
Q

antiparallel

A

-2 back bones in a DNA double helix run in opposite directions

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2
Q

what direction do the antiparallel strands run from

A

5- prime to 3- prime

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3
Q

what is 3 prime

A

-the hydroxyl group of the pentose sugar

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4
Q

what is 5 prime

A

-the phosphate group

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5
Q

what’s a polynucleotide

A

-when 3 or more nucleotides are joined together with phosphodiester bonds

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6
Q

what is the relationship between AT and CG and AU called

A

-complementary base pair

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7
Q

why is the bonding between nucleotides called phosphodiester

A

-the phosphate forms an ester bond with the hydroxyl group of the 3rd carbon on adjacent nucleotide
-the phosphate also forms another ester bond to the 5th carbon of pentose

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8
Q

what do you call a nucleotide with one or more phosphates attached to it

A

-phosphorylated nucleotide

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9
Q

what is ATP structure

A

-Adenosine triphosphate
-adenosine is made from ribose (sugar) and adenine (base)
-sugar combined with 3 phosphate groups on 5th carbon

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10
Q

properties of the phosphate

A

-always the same
-acid and negatively charged
-looses H in ester bond with pentose sugar
-forms ester bonds with 3rd and 5th carbon

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11
Q

properties of pentose sugar

A

-can be deoxyribose or ribose
-5 carbon atoms
-looses 2 OH groups in reactions

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12
Q

difference between deoxyribose and ribose molecular structure

A

-deoxyribose has H on 2nd carbon wheras ribose has OH

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13
Q

difference between deoxyribose than ribose

A

-deoxyribose is more stable than ribose

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14
Q

what does a phosphate group contain

A

-C, H, O, N, P

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15
Q

types of bases

A

-purine
-pyrimidine

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16
Q

difference between purine and pyrimidine

A

-purine has a double carbon ring structure
-pyrimidines have a single carbon ring structure and are smaller
they always pair together

17
Q

what bases are purine

A

-adenine
-guanine

18
Q

what bases are pyrimidine

A

-thymine
-cytosine
-uracil

19
Q

DNA

A

-double stranded
-deoxyribose as sugar
-base ATCG
-sugar phosphate backbone
-can last for a long time
-read by polymerase
-stores genetic info
-is read 3 prime to 5 prime

20
Q

RNA

A

-single stranded
-ribose as sugar
-bases AUCG
-sugar phosphate backbone
-doesn’t usually last for a long time
-read by ribosomes
-stores info about protein structure
-formed in 5 prime to three prime
-modified 5 prime cap and 3 prime poly- A tail

21
Q

whats a nucleotide

A

-monomer from which nucleic acids are made