Nucleic Acid Synthesis Inhibitors Flashcards

1
Q

Quinolones AE

A

Chelates
Achilles and Rotator Cuff tendonitis and rupture
QT prolong

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2
Q

Nitrofurans drugs

A

Nitrofurantoin
Macrobid
Macrodantin

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3
Q

Nitrofurans used for?

A

Uncomplicated UTI

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4
Q

Nitroimidazoles drug

A

Metronidazole

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5
Q

Metronidazole AE

A

Recycling of drug
Furry tongue
SJS
Metallic taste

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6
Q

Rifapentine

A

Long acting agent

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7
Q

Rifabutin

A

Less P450

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8
Q

Rifamycins AE

A

Orange excretions

Hepitatis

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9
Q

Folic Acid Importance

A

Required for purine, nucleic acids and amino acid synthesis

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10
Q

Silver Sulfadiazine use

A

Burns

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11
Q

Sulfacetamide use

A

Ophthalmic

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12
Q

Dapsone use

A

Leprosy

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13
Q

Sulonamide oral use

A

Cleanse GI

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14
Q

Antimetabolites AE

A

Renal crystals if dehydrated
SJS
Hemolytic anemia

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15
Q

SMZ:TMP

A

Administered 5:1

Insitu 20:1

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16
Q

Macrocyclic drug

A

Fidaxomicin