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ID Final > Antibacterial Pharmacology > Flashcards

Antibacterial Pharmacology Flashcards

1
Q

Ehrlich coined

A

chemotherapy

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2
Q

Cell Wall Synthesis Inhibitors

A

Penicillins
Cepalosporins
Monobactams
Carbapenems

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3
Q

Protein synthesis Inhibitors

A 
Tetracyclines
AG
Macrolides
Stregtogramins
Chloramphenicol
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4
Q

Nucleic acid function or synthesis Inhibitors

A

Rifampin
Quinolones
Antimetabolite sufonamides
Trimethoprim

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5
Q

Cell membrane permeability/function Inhibitors

A

Polymicin
Nystatin
Amphotericin B

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6
Q

Time dependent defined

A

Blood levels is >MIC for 40-50% time of the dosing interval

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7
Q

Concentration dependent defined

A

AUC >25 times MIC or Peak >10 times MIC

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8
Q

Renal Disease

A

AG

Vanco

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9
Q

Hepatic Disease

A

Erthromycin

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10
Q

6 P’s

A 
Penetration
Porins
Pumps
PBPs
Penicillinase 
Pathway
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11
Q

Plasmids

A

Extrachromosomal DNA

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12
Q

Mobile DNA

A

DNA from plasmid or chromosomes is relocated to a new location

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13
Q

Transposons

A

Larger blocks of genetic material that are moved around

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14
Q

Transposition

A

Movement within the same genome

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15
Q

Integrons

A

Smaller more specific segment of mobile DNA along the transposon

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16
Q

Bacteriophages

A

A virus that infects the bacteria

17
Q

Acute Vaccines

A

Switching off genes

ID Final (31 decks)

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