30S Inhibitors Flashcards
1
Q
50S is responsible for?
A
Biochemical tasks
2
Q
30S is responsible for?
A
Recognition task
3
Q
Peptidyl transferase
A
Catalyzes formation of the new peptide bond to elongate the polypeptide
4
Q
Gentamicin is NOT used?
A
In Neisseria,
N. meningitis or Legionella bc of the release of an LPS endotoxin can cause shock in a pt
5
Q
AG special features
A
Concentration dependent
Post-antibiotic effect
IV/IM
6
Q
AG AE
A
Nephrotoxicity
Ototoxicity
7
Q
Doxycycline is used in?
A
CA-MRSA
8
Q
TC, tigecycline and Quinolones have what AE?
A
Chelating with metals
9
Q
Generally TC do not?
A
Penetrate well into CNS/CSF, except Mino
Widely distrubuted though so cover atypicals
10
Q
Minocycline AE
A
Black/blue pigmentation of the skin
