non_coding RNAs lecture Flashcards
ribozymes are RNA molecules with what type of activity
catalytic
SmY RNAs are families of ncRAS in nematodes that are thought to be involved in special type of RNA splicing. Based on this function, SmY RNAs are most likely members of which category of ncRNAS
snRNA- associates with proteins to form subunits of the splice some, which splices pre-mRNA in eukaryotes
What feature of CRISPR-Cas system cuts DNA sequences they target?
Cas 9- functions as endonuclease that makes double stranded breaks in bacteriophage DNA
in order of her occurrence what are the steps in RNA interference
processing of RNA transcript by DGCR8, transport to cytoplasm, processing by Dicer, binding to RISC, binding to target mRNA
which of these types of ncRNA normally originate form s source other than the cells in which they act?
siRNA- regulate expression and degradation of mRNAs
select the ncRNA that coats one to the X-chromosomes in mammals to create Barr body
Xist RNA
how does the ncRNA HOTAIR inhibit transcription
by causing chromatin modification
which of the following types of ncRNAs act to prevent the movement of transposable elements?
piRNA- prevents movement of transposable elements
the CRISPR-Cas system in bacteria is most tsiilar to what system in vertebrates?
immune system
ribozyme
RNA molecule with a catalytic function
small nuclear RNA (snRNA)
associate with proteins to form subunits of the splice some, which splices pre-mrnas in eukaryotes
transfer RNA (tRNA)
recognize mRNA codons during translation and carry the appropriate amino acids
Xist RNA
coats one of the X chromosomes in female mammals and plays role in its compaction and resulting inactivation (Barr body)
Telomerase RNA component (TERC)
facilitates and binding of a telomerase to the telomere and acts as a template for DNA replication
HOTAIR
alters chromatin structure and thereby represses transcription by guiding histon-modifying enzymes to target genes
