linkage and mapping Flashcards

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1
Q

genetic linkage

A

DNA sequences that are close together on a chromosome to be inherited together during meiosis phase of sexual reproduction

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2
Q

which of the following defines genetic linkage?
A. two or more genes that are physically connected on a chromosome
B. genes that are transmitted to the next generation as a group
C. process by which genetic information is exchanged between homologous chromosomes
D. A and B

A

two or more genes that are physically connected on a chromosome and genes that are transmitted to the next generation as a group

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3
Q

linkage group

A

2 or more genes that do not independently assort and tend to be transmitted together

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4
Q

which of the following best describes a linkage group

A

a chromosome

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5
Q

Assume that genes F and G are located on the same chromosome. On one chromosome alleles F and G are found, while the homologue contains alleles f and g. Which of the following would be an example of a recombination event?
A. alleles F and G together on one chromosome
B. alleles f and g together on one chromosome
C. alleles F and g together on one chromosome
D. alleles f and G together on one chromosome
E. C and D

A

alleles F and g together on one chromosome and alleles f and G together on one chromosome

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6
Q

which of the following is a statistical test used to determine if 2 genes are linked or assorting independently

A

chi-square test- used to determine if the outcome of a cross is consistent with linkage or with independent assortment

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7
Q

while mapping 2 genes in Drosophila, you observe 30 recombinants among 200 total offspring. What is the distance between these genes?

A

15 map units

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8
Q

map distance formula

A

(# of recombinant offspring/ total # of offspring) x 100

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9
Q

a map distance between genes indicates which if the following

A

23.6% of the offspring exhibit recombination between 2 genes

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10
Q

in a mapping experiment, which phenotype should occur most often in the F2 offspring

A

parental phenotypes as they are the most frequent

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11
Q

crossover

A

single cell divides twice to produce 4 cells containing 1/2 the original amount

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12
Q

a crossover in meiosis is na exchange of genetic material between

A

non-sister chromatids of homologous chromosomes

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13
Q

synteny

A

physical linkage of genes into the same chromosomee

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14
Q

the number of linkage groups=

A

the number of types of chromosomes of the species

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15
Q

likehood of crossing over depends on

A

it depends on the distance between the two genes

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16
Q

chi square analysis

A

method used to determine the outcome of a cross is consistent with linkage or with independent assortment

17
Q

recombination

A

physical change of the DNA from one chromosome to the other

18
Q

genetic mapping

A

purpose is to determine the linear order of linked genes along the same chromosome

19
Q

which crosses involving linked genes occur less frequently

A

double crossover

20
Q

double crossover

A

separate the gene in the middle from the other two genes at either end

21
Q

genome

A

haploid set of chromosomes

22
Q

recombination

A

exchange of genetic material between different organisms which lead to production of offspring with combinations of traits that differ from those found in either parent

23
Q

crossover

A

swapping of genetic material that occurs in the germ line