NMJ blockers

Question 1

goal/function

Answer 1

block transmission at NMJ, paralysis of skeletal muscle

Question 2

these drugs have no effect on

Answer 2

conciseness or pain!

Question 3

depolarizing

Answer 3

succinylcoa (no reverse), cause depolarization and long refractory period, then desensitization of receptor, no fade phenom

Question 4

non depolarizing

Answer 4

competitive, 1 moles block R, 70% needed for response. fade phenom> monitor TOF

Question 5

sequence

Answer 5

larger muscles last (offset opposite onset order)

Question 6

adverse non depol

Answer 6

tachycardia, HTN, histamine, acute quad sequence

Question 7

depol side effects

Answer 7

BAD, hyperkal, bradychardia, malig hen, anaphylaxis

Question 8

reverse drug for non depil

Answer 8

acetyl choline inhib