gas exchange Flashcards
gas exchange def
movement of gas between environment and blood
solubility in plasma
proportional to partial pressure (Henry law)
co2 vs 02 solubility
CO2 dissolves at a much higher rate
Co2 vs 02 driving force
much larger for 02 (60-100 vs 46-40)
rate of diffusion Co2 vs 02
diffuse at similar rates
capilary transit time
.75 sec (normally equilibrium at .3 seconds, so extra time)
diffusion limited capacity
CO.
perfusion limited diffusion capacity
nitrogen, uptake depends on blood flow
diffusion capacity for 02 and CO2 in healthy
perfusion!
PA02=
Pi02-PaCo2/.8
A-aDO2
Dif in all gas/mixed, means vent and perfusion isn’t perfect. high=problme
02 transport
most on hemoglobin, creates pressure gradient for some to diffuse
right shift
release/less strong bind of 02 to hemoglobin
things that cause right shift
Temp, PH, PCo2, DPG
things that cause left shift
CO poisin, NO, fetal hemoglobin, methomeglobonin