ILD/occupational

Question 1

PFTs in ILD

Answer 1

how compliance, increased fibrosis, decreased TLC, increased elastic recoil, decreased DLCO

Question 2

path for ILD

Answer 2

lung injury> Mphage> tcell activation»» fibrosis

Question 3

T cell activation outcomes

Answer 3

T cell proliferation, monocle recruitment, B cells

Question 4

fibrosis without T cell activation

Answer 4

TGF-B» fibroblast

Question 5

gas exchange in ILD

Answer 5

less alveoli, less ventilation, v/q mismatch» hypoxemia

Question 6

other PE findings with ILD

Answer 6

alopecia, tachycardia, tachypnea, clubbing, crackles/rale

Question 7

honeycomb signifies

Answer 7

traction bronchiectasis, chronic

Question 8

nodules signifies

Answer 8

inflam/infection

Question 9

ground glass signifies

Answer 9

infection/inflam

Question 10

complications of ILD

Answer 10

resp fail, exaceterbations, pneumothorax, PE, lung cancer

Question 11

idiopathic pulm fibrosis

Answer 11

1 ILD, smoke, progressive, relentless» resp failure

Question 12

sarcoidosis general

Answer 12

granulomas. women, AA, Irish, stand, exam immune response, variable course. T: corticosteroids

Question 13

pneumoconioses

Answer 13

dust/inflam… assestos, silicosis, coal.

Question 14

hypersensitivity pneumonitis

Answer 14

immune sexton to organic molecular.e extrinsic allergic alveoli’s

Question 15

direct ILD

Answer 15

direct lung injury (silo, metal fume, byssinosis)

Question 16

asbestosis

Answer 16

lower love, honeycomb, asbestos bodies,

Question 17

silicosis

Answer 17

quarts exposure, small matrices, upper lobe, hilarious LN, central cavitation/TB

Question 18

asbestosis complications

Answer 18

pleural Jeff, pleural plaque, lung car, mesothelioma

Question 19

sarcoidosis histo

Answer 19

well circumscribed non necrotizing granola, bronchovasc bundle, rule out Rb/berylloma, low background inflammation

Question 20

granulomatosis with polyangitis

Answer 20

vasculitis.necrotizing. glomerulitis, C ANCA… ulceration, t: immunotherapy.

Question 21

langerhan cell histocytosis

Answer 21

prolific langerhan cells, syndrome or lung limited (smoking), most recover

Question 22

langerhan cell histocytosis

Answer 22

birbeck granules, nuclear grooves, healed fibrosis

Question 23

idiopathic pulm fibrosis

Answer 23

usual interstitial pneumonia pattern, bad survival, lower lobe.

Question 24

IPF history

Answer 24

heterogen interstitial fibrosis fibroblast cocci, honeycomb.

Question 25

cryptogenic organizing pneumonia

Answer 25

organizing, non infectious, drug prob related, cough/dyspnea, fever, WL

Question 26

acute interstitial pneumonia

Answer 26

diffuse alveolar damage, looks like ARDS,

Question 27

desquam interstitial pneum

Answer 27

smoking, alv Mphage,fibrosis, t: steroids and quit smoking