lung tumors/cancer

Question 1

clin presentation of lung cancer

Answer 1

WL, fever, cough, mets, paraneoplastic

Question 2

risk factors

Answer 2

smoke, occupation, radiation

Question 3

diagnosis

Answer 3

sputum, aspiration, biopsy (depends on cancer location)

Question 4

squamous cell cancer

Answer 4

smoking related, central lesion, hypercalcemia

Question 5

squamous histo

Answer 5

precursor lesions (met>dys>insutu>)pleomorphic nuclei, keratin pearls, intracell bringe, TTF1- neg

Question 6

adenocarcinoma

Answer 6

increasing incidence, most common in USA, kiwi smoking association, peripheral tumor

Question 7

ademon histo

Answer 7

glands, mucin, TFF1 positive

Question 8

small cell

Answer 8

very aggressive, large central mass, paraneoplastic (SIADH)… SMOKING

Question 9

Histo small cell

Answer 9

small blue cells, stippled/molding, neuroendocrine, can be TFF1 positive

Question 10

pleural tumors

Answer 10

usually mets (lung/BC), may cause pleural effusion, primary may be benign

Question 11

pleural plaque

Answer 11

asbestosis, no clin signif

Question 12

malignant mesothelioma

Answer 12

asbestos exposure, not smoking

Question 13

mesothelioma histo

Answer 13

diffuse, rind like, firm/white

Question 14

oral cavity tumors

Answer 14

mostly squamous cell.. erythroplakia/leukoplakia

Question 15

nasopharyngeal tumors

Answer 15

EBV, upper cervial LN, history: keritizing or not, blue cells but more cytoplasm

Question 16

larynx tumors

Answer 16

mostly squamous cell (smoking, HPV risk)

Question 17

how is lung cancer found (3)

Answer 17

symptom, screening, incidental

Question 18

pan coast tumor

Answer 18

apical, NSCLC, brachial plexus symptoms, invade bone, Horner syndrome

Question 19

Horner syndrome

Answer 19

ptosis, mitosis, anhydrous, enhopthalmos

Question 20

nodule workup

Answer 20

radio, ct, PET.CT, brain…

Question 21

carcinoid

Answer 21

neuroendocrine, low malig

Question 22

hamartoma

Answer 22

benign, trapped resp epithelium

Question 23

calcification of nodule

Answer 23

suggests benign, old granuloma