intro to general anesthetic Flashcards
characteristics of general
drug induced, reversible, unconscious, amnesia, analgesia, alkalesia
what produce unconscious/ amnesia
hinted or IV
inhaled anesthetics divided into
volatile and gas
volatile drugs
desflurane, isodlurane, sevo
gas inhaled drug
NO
IV drugs
dex, etomidate, ketamine, propofol
mech of inhaled
not fully understood, but hydrophobicity, polarity, and chilarity
target types
potentiate inhibition or antag
potentiate inhibition targets
gaba/glycine or a2
untag target
nmda
what targets gaba/glycine
volatiles, propofol, etomidate
what targets a2
dex
what targets NMDA
no, ketamine
gaba/glycine effect
enhance inhibitors of synaptic cleft, inhib inhibition.. increase unorganized neural activity leads to uncouncous
immobility
needs to hit spinal cord, higher MAC
MAC
more potent, lower mac
clearance
just breath it off, no real metab
speed of onset
faster onset/onset of low solubility
equilib
Dif concentration but equal PP in air and blood