Nitrofurantion Flashcards
1
Q
High or low serum and tissue conc?
A
Low
2
Q
High or low urine conc?
A
High
3
Q
Excretion rate? Related to?
A
Linear
Creatine clearance
4
Q
Can cause ___________ especially in renal insufficiency
A
peripheral neuropathy
5
Q
Pulmonary rxs:
Acute - fever, cough, ___________, eosinophilia, __________
A
dyspnea
infiltrate
6
Q
Subacute and chronic rxs
Cough, ___________
A
dyspnea
infiltrate
7
Q
Unclear MOA. May interfere with early bacterial carbohydrate metabolism by inhibiting _________
May be due to production of ______, free radical
A
Acetyl coA
5-nitro anion
