Neurotransmitters Part 2

Question 1

Example of Metabotropic Receptor-

Answer 1

Beta1 Adrenergic

Question 2

B1: — greater affinity than —

Answer 2

Epi
NE
(Inc. Heart Rate and cardiac contractility)

Question 3

Termination of Transmitter Action (3)

Answer 3

reuptake
breakdown
diffusion

Question 4

reuptake

Answer 4

NT can be returned to axon terminals for reuse or transported into glial cells

Question 5

breakdown

Answer 5

enzymes inactivate NT

Question 6

diffusion

Answer 6

NT can diffuse out of the synaptic cleft

Question 7

Nerve Gas Insecticides

AchE

Question 8

Small molecule NT made in the

Answer 8

terminal

Question 9

Peptides made in the

Answer 9

cell body

Question 10

Classifying Neurons by Transmitter

ACh: class

Answer 10

cholinergic

Question 11

Classifying Neurons by Transmitter

DA: class

Answer 11

dopaminergic

Question 12

Classifying Neurons by Transmitter

NE: class

Answer 12

noradrenergic

Question 13

Classifying Neurons by Transmitter

Glu: class

Answer 13

glutamatergic

Question 14

Classifying Neurons by Transmitter

GABA: class

Answer 14

GABAergic

Question 15

Classifying Neurons by Transmitter

peptide: class

Answer 15

peptidergic

Question 16

Lidocaine-

Answer 16

VGNa channel blocker

Question 17

Tetrodotoxin-

Answer 17

VGNa channel blocker

Question 18

Caffeine- increase

Answer 18

neuronal excitability

Question 19

Drugs- (3)

Answer 19

Cocaine, Amphetamines, SSRI

Question 20

block reuptake (2)

Answer 20

SSRIs (5HT)

Cocaine (DA, NE)

Question 21

Increase release, block reuptake (2)

Answer 21

Ecstasy

Amphetamine (DA, NE, 5HT)

Question 22

Potentiation of synapses: — — potentiation

Answer 22

long term

Question 23

Potentiation of synapses: increase… (2)

Answer 23

Increase the response in the postsynaptic neuron

Increase the release of NT (glutamate) from presynaptic neuron

Question 24

Increase the response in the postsynaptic neuron (2)

Answer 24

• More receptors

* Phosphorylation of proteins to increase response