Neurotransmitters Part 2 Flashcards by sophie rosen

Q

Example of Metabotropic Receptor-

A

Beta1 Adrenergic

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Q

B1: — greater affinity than —

A

Epi
NE
(Inc. Heart Rate and cardiac contractility)

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Q

Termination of Transmitter Action (3)

A

reuptake
breakdown
diffusion

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Q

reuptake

A

NT can be returned to axon terminals for reuse or transported into glial cells

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Q

breakdown

A

enzymes inactivate NT

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Q

diffusion

A

NT can diffuse out of the synaptic cleft

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Q

Nerve Gas Insecticides

AchE

A

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Q

Small molecule NT made in the

A

terminal

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Q

Peptides made in the

A

cell body

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Q

Classifying Neurons by Transmitter

ACh: class

A

cholinergic

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Q

Classifying Neurons by Transmitter

DA: class

A

dopaminergic

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Q

Classifying Neurons by Transmitter

NE: class

A

noradrenergic

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Q

Classifying Neurons by Transmitter

Glu: class

A

glutamatergic

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Q

Classifying Neurons by Transmitter

GABA: class

A

GABAergic

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Q

Classifying Neurons by Transmitter

peptide: class

A

peptidergic

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Q

Lidocaine-

A

VGNa channel blocker

Q

Tetrodotoxin-

A

VGNa channel blocker

Q

Caffeine- increase

A

neuronal excitability

Q

Drugs- (3)

A

Cocaine, Amphetamines, SSRI

Q

block reuptake (2)

A

SSRIs (5HT)

Cocaine (DA, NE)

Q

Increase release, block reuptake (2)

A

Ecstasy

Amphetamine (DA, NE, 5HT)

Q

Potentiation of synapses: — — potentiation

A

long term

Q

Potentiation of synapses: increase… (2)

A

Increase the response in the postsynaptic neuron

Increase the release of NT (glutamate) from presynaptic neuron

Q

Increase the response in the postsynaptic neuron (2)

A

More receptors

* Phosphorylation of proteins to increase response