Neurotransmitters

Question 1

Hypocretin

Answer 1

exctiatory neurotransmistter that regulates wakefulness, sleep, appetite. AKA orexin (greek for appetite). Made by neurons in te hypothalamus that produce hypocretin. Hypocretin 1 and 2 .

Question 2

GABA

Answer 2

Inhibitory NT, can cause influx of Cl- to HYPERPOLARIZE the cell, leading to DECREASED neuronal firing

Question 3

Glycine

Answer 3

Inhibitory NT, can cause influx of Cl- to HYPERPOLARIZE the cell, leading to DECREASED neuronal firing

Question 4

Glutamate

Answer 4

Excitatory NT, which can cause influx of Na+ or Ca++ to DEPOLARIZE the cell, leading to INCREASED neuronal firing

Question 5

Aspartate

Answer 5

Excitatory NT, which can cause influx of Na+ or Ca++ to DEPOLARIZE the cell, leading to INCREASED neuronal firing

Question 6

How Do 2nd messenger systems work?

Answer 6

Example: G protein linked. NT binds to receptor, causing a change in the receptor for G coupled proteins to bind. Skip a few steps, leads to a change in receptor gene expression on the DNA level. This could be either desensitization or down regulation.