Mechanisms for Disease

Question 1

Mechanism for OCD

Answer 1

Serotonergic Dysfunction. hyperactivity in caudate

Question 2

During reappraisal tasks, hyperreactivity in the amygdala

Answer 2

Avoidant Personality Disorder

Question 3

Dysfunctional Oxytocinergic Functioning

Answer 3

Attachment and anxiety regulation

Question 4

Variation in MAO-A including long alleles of the MAOA-uVNTR promoter polymorphism.

Answer 4

Panic Disorder with agoraphobia

Question 5

Catecholaminergic disruption

Answer 5

Manic Episode

Question 6

cholinergic dysfunction

Answer 6

Bipolar Depression

Question 7

Reduced lateral prefrontal-amygdala communication

Answer 7

borderline

Question 8

Mechanism for PMDD

Answer 8

altered sensitivity to progesterone and estrogen.

Question 9

Neural circuity for depression

Answer 9

decreased function in noradrenergic locus coeruleus, serotoninergic dorsal raphe and median raphe, and dopaminergic ventral tegmental area.

Question 10

Polymorphism in contactin-associated protein-like 2-gene (CNTNAP2)

Answer 10

Selective mutism

Question 11

Disturbed amygdala prefrontal cortex circuitry function during face emotion processing

Answer 11

dmdd

Question 12

The autism has levels of what NT attached with platelets?

Answer 12

serotonin

Question 13

Bipolar Disorder SB100

Answer 13

There is a decrease in the number of S100B immune-positive oligodendrocytes in hippocampus of patients with bipolar disorder. There is a reduction in the number of oligodendroglia in dorsolateral prefrontal cortex white matter in patients with bipolar disorder.

Question 14

Reduced number of Purkinje cells?

Answer 14

Autism Spectrum Disorder

Question 15

decrease in the levels of norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG) in the urine and cerebrospinal fluid.

Answer 15

Anorexia Nervosa

Question 16

Impairment in excitation-inhibitory balance due to altered NMDA receptor signaling

Answer 16

Schizophrenia

Question 17

MAPT mutation

Answer 17

lewy body