Genetics Tests

Question 1

What test do you use for DNA testing of chromosomes?

Answer 1

FISH (fluorescence in situ hybridization)

Question 2

Test to consider in those with ID like seen in autism:

Answer 2

FMR-1 DNA test (fragile x )

Question 3

Essential Tremor: how is it inherited?

Answer 3

Autosomal dominant.

Question 4

MECP2

Answer 4

Rett Syndrome

Question 5

Chromosome 15 dysfunction

Answer 5

Angelman Syndrome, inherited from the father

Question 6

Val/Val and Val/Met genotypes for COMT (Val158Met)

Answer 6

More likely to have cannabis induced psychotic disorder

Question 7

(5HTTLPR)

Answer 7

has been associated with an increased risk for nicotine dependence

Question 8

G allele genotype (GG/AG) in the A118G SNP of OPRM1

Answer 8

has been associated with increased craving and excess mesocorticolimbic activation to alcohol use.

Question 9

X-linked dominant (lethal in males) syndrome characterized by agenesis of the corpus callosum, developmental delay, and infantile spasms

Answer 9

Aicardi syndrome

Question 10

Which chromosome is Frontotemporal dementia on?

Answer 10

FTDP-17 cases show neuronal and/or glial inclusions that stain positively with antibodies raised against the microtubule-associated protein tau (MAP-T). The MAP-T gene for encoding tau protein is located on chromosome 17q21

Question 11

What chromosome linked with early onset alzheimer’s dz?

Answer 11

19