Neuropathic pain Flashcards

1
Q

common occurences of neuropathic pain

A

herpes zoster “shingles”
diabetes d/t increased glucose (neurotoxic)
cancer
chemo/radiation

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2
Q

neuropathic meds

A

TCAs
SNRIs

antiepileptics:
carbamazepine
gabapentin
pregabalin

*MUST be used in conjunction w/pain med

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3
Q

neuropathic mechanism of action for carbamazepine
gabapentin
pregabalin

A

suppress the spontaneous firing of damaged neurons

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4
Q

issues w/carbamazepine

A

bone marrow suppressor (decreases RBC, WBC, platelets)
steven johnsons rash
interactions: warfarin, grapefruit juice, oral contraceptives

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5
Q

issues w/gabapentin

A

few side effects, no significant interactions
sedation
fatigue
ataxia

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